Results 81 to 90 of about 10,800,125 (320)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Metamagnets in uniform and random fields
, 1998 We study a two-sublattice Ising metamagnet with nearest and next-nearest-neighbor interactions, in both uniform and random fields. Using a mean-field approximation, we show that the qualitative features of the phase diagrams are significantly dependent ...
Galam, Serge +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Uniform distribution in the n-dimensional torus
Lietuvos Matematikos Rinkinys, 2010 Limit distribution of endomorphisms of the n-dimensional torus is examined. The obtained result generalizes earlier results of the authors.
Gintautas Misevičius +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
GENERATION OF PSEUDORANDOM NUMBERS
Современная наука и инновации, 2022 The article is devoted to algorithms for generating pseudorandom numbers according to certain laws of distribution of random numbers. The problems of generation of pseudorandom uniformly distributed integers of large size and real numbers, real numbers ...
Gladskih Yur’evich Gladkih
doaj
Correlation between Risk Aversion and Wealth distribution
, 2003 Different models of capital exchange among economic agents have been proposed recently trying to explain the emergence of Pareto's wealth power law distribution. One important factor to be considered is the existence of risk aversion.
Aoyama +18 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Study on probabilistic multi- objective linear fractional programming problems under fuzziness
International Journal of Industrial Engineering and Production Research, 2020 This paper deals with a multi- objective linear fractional programming problem involving probabilistic parameters in the right- hand side of the constraints.
Hamiden Khalifa, E. E. Ammar
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