Results 61 to 70 of about 708,407 (265)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
EXTENSION OF STARLIKE FUNCTIONS TO A FINITELY PUNCTURED PLANE
Проблемы анализа, 2017 We consider a sequence of functions which are starlike in the unit disk and their logarithmic derivatives are meromorphic with a finite number of simple poles in any boundary domain.
D. V. Prokhorov
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Nano-ZnO Particles’ Effect in Improving the Mechanical Response of Mg-3Al-0.4Ce Alloy
Metals, 2016 Magnesium based nanocomposites, due to their excellent dimensional stability and mechanical integrity, have a lot of potential to replace the existing commercial Al alloys and steels used in aerospace and automotive applications.
Sravya Tekumalla +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
On strong uniform distribution IV
Journal of Inequalities and Applications, 2005 Let be a strictly increasing sequence of natural numbers and let be a space of Lebesgue measurable functions defined on . Let denote the fractional part of the real number . We say that is an sequence if for each we set , then , almost everywhere
Nair R
doaj
On Uniform Distribution of Algebraic Numbers [PDF]
Proceedings of the American Mathematical Society, 1953 Let K be an algebraic number field of degree n + 1 over the rational field R. The conjugates of K are denoted by K(?), , I K(n), it being supposed that K M K(cl are real, K(r?l+), * , K(n) are complex, and moreover that for k =r1+ *, ri +r2 the fields K(k) and K(k+r2) are obtainable from one another by interchanging i( = (1)1/2) and -i (here r1+2r2=n).
openaire +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source