Results 41 to 50 of about 2,778,281 (282)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

On the moments of random variables uniformly distributed over a polytope

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
Suppose X=(X1,X2,…,Xn) is a random vector uniformly distributed over a polytope. In this note, the author derives a formula for E(XirXjs…), (the expected value of XirXjs…), in terms of the extreme points of the polytope.
S. Paramasamy
doaj   +1 more source

Some limit theorems for ratios of order statistics from uniform random variables

open access: yesJournal of Inequalities and Applications, 2017
In this paper, we study the ratios of order statistics based on samples drawn from uniform distribution and establish some limit properties such as the almost sure central limit theorem, the large deviation principle, the Marcinkiewicz-Zygmund law of ...
Shou-Fang Xu, Yu Miao
doaj   +1 more source

Mixture Representations for Generalized Burr, Snedecor–Fisher and Generalized Student Distributions with Related Results

open access: yesMathematics, 2023
In this paper, the representability of the generalized Student’s distribution as uniform and normal-scale mixtures is considered. It is also shown that the generalized Burr and the Snedecor–Fisher distributions can be represented as the scale mixtures of
Victor Korolev, Alexander Zeifman
doaj   +1 more source

Uniform Random Sample and Symmetric Beta Distribution [PDF]

open access: yes, 2013
N.L. Johnson and S. Kotz introduced in 1990 an interesting family of symmetric distributions which is based on randomly weighted average from uniform random samples.
Homei, Hazhir
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Natural Test for Random Numbers Generator Based on Exponential Distribution

open access: yesMathematics, 2019
We will prove that when uniformly distributed random numbers are sorted by value, their successive differences are a exponentially distributed random variable Ex(λ).
Ilija Tanackov   +6 more
doaj   +1 more source

Persistent spin currents in an elastic Landau system

open access: yes, 2013
We consider a neutral particle with permanent magnetic dipole moment in an elastic medium with the presence of a uniform distribution of screw dislocations interacting with a radial electric field.
Bakke, K., Furtado, C.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Effects of Random Values for Particle Swarm Optimization Algorithm

open access: yesAlgorithms, 2018
Particle swarm optimization (PSO) algorithm is generally improved by adaptively adjusting the inertia weight or combining with other evolution algorithms.
Hou-Ping Dai   +2 more
doaj   +1 more source

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