Results 91 to 100 of about 354,562 (267)
A uniform quantitative stiff stability estimate for BDF schemes [PDF]
Opuscula Mathematica, 2006 The concepts of stability regions, \(A\)- and \(A(\alpha)\)-stability - albeit based on scalar models - turned out to be essential for the identification of implicit methods suitable for the integration of stiff ODEs.
Winfried Auzinger, Wolfgang Herfort
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Stability of common fixed points in uniform spaces
Fixed Point Theory and Applications, 2011 Stability results for a pair of sequences of mappings and their common fixed points in a Hausdorff uniform space using certain new notions of convergence are proved. The results obtained herein extend and unify several known results.
Singh Shyam +2 more
doaj
Stability of second-order recurrences modulo pr
International Journal of Mathematics and Mathematical Sciences, 2000 The concept of sequence stability generalizes the idea of uniform distribution. A sequence is p-stable if the set of residue frequencies of the sequence reduced modulo pr is eventually constant as a function of r.
Lawrence Somer, Walter Carlip
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Uniform Asymptotic Stability of Solutions of Fractional Functional Differential Equations
Abstract and Applied Analysis, 2013 Some global existence and uniform asymptotic stability results for fractional functional differential equations are proved.
Yajing Li, Yejuan Wang
doaj +1 more source