Results 31 to 40 of about 13,227 (303)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Diseño de uniformes para la Unidad Educativa Experimental Pedro Fermín Cevallos
, 2008 1. El problema. 2. Marco teórico. 3. Metodología. 4. Propuesta. 5. Conclusiones y recomendacionesA lo largo de la historia se han creado uniformes de todo tipo. Uniformes que expresan funciones, profesiones, vocaciones, opciones de vida y elecciones.
Viera Núñez, Martha Paola
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Implementación de una organización efectiva en uniformes GIMA [PDF]
, 2021 Autogestión EmpresarialMediante el presente proyecto se pretende la reestructuración en el área administrativa de la empresa Uniformes y Confecciones GIMA favoreciendo su ampliación en el nicho de mercado, mediante procesos como lo son la ...
Vargas-Olarte, María Paula
core
Revista Portuguesa de Medicina Geral e Familiar, 2007 Os Requisitos Uniformes foram criados para ajudar autores e editores a criar e distribuir relatórios de estudos biomédicos precisos, claros e facilmente acessíveis.
doaj +1 more source
Holographic Uniformization [PDF]
Communications in Mathematical Physics, 2013 We derive and study supergravity BPS flow equations for M5 or D3 branes wrapping a Riemann surface. They take the form of novel geometric flows intrinsically defined on the surface. Their dual field-theoretic interpretation suggests the existence of solutions interpolating between an arbitrary metric in the UV and the constant-curvature metric in the ...
Anderson, Michael T. +3 more
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Preliminar de rendimiento de líneas uniformes de arroz.
Agronomía Mesoamericana, 2016 Con el objetivo de seleccionar y poner a disposición del Programa de Granos Básicos un germoplasma promisorio de arroz, con alto potencial de rendimiento, resistente o tolerante a enfermedades fungosas, principalmente a piricularia y buena arquitectura ...
Wilfredo Castañeda, Luis Guerrero
doaj +1 more source