Results 31 to 40 of about 1,928 (262)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Versión 1993 de los requerimientos uniformes de publicación
Biomédica: revista del Instituto Nacional de Salud, 1994 A mediados de este ano, el lnternational Committee of Medical Journal Editors publicó una quinta versión de los requerimientos uniformes para someter manuscritos (1).
A. Loría, R. Lisker
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Uniformes: Bem estar e segurança para trabalhadores de Limpeza Pública
ModaPalavra e-periódico, 2011 Este trabalho avalia os uniformes profissionais utilizados na área de limpeza pública, levando em consideração alguns aspectos para a produção. Tais como os riscos de trabalho; o estudo de aspectos de ergonomia; de modelagens; e a seleção de materiais ...
Dulce Maria Holanda Maciel +1 more
doaj +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Preliminar de rendimiento de líneas uniformes de arroz.
Agronomía Mesoamericana, 2016 Con el objetivo de seleccionar y poner a disposición del Programa de Granos Básicos un germoplasma promisorio de arroz, con alto potencial de rendimiento, resistente o tolerante a enfermedades fungosas, principalmente a piricularia y buena arquitectura ...
Wilfredo Castañeda, Luis Guerrero
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Fantasias da igualdade: uniformes escolares e democratização no Brasil
Cadernos de História da Educação, 2016 Resumo O artigo examina as diferentes configurações das práticas de uso dos uniformes escolares no período de 1948 a 1971, no caso brasileiro. Despertando os mais diversos sentimentos, pretendendo "apagar as diferenças" sócio-econômicas evidenciadas ...
Katiene Nogueira da Silva +1 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source