Results 51 to 60 of about 59,818 (241)

On the generic behavior of the metric entropy, and related quantities, of uniformly continuous maps over Polish metric spaces

Mathematische Nachrichten, 2022
AbstractIn this work, we show that if f is a uniformly continuous map defined over a Polish metric space, then the set of f‐invariant measures with zero metric entropy is a set (in the weak topology). In particular, this set is generic if the set of f‐periodic measures is dense in the set of f‐invariant measures.
Carvalho, Silas L., Condori, Alexander
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Assessment of the Magnitude and Extent of Climate Change in Different Regions of Iran [PDF]

محیط زیست و توسعه فرابخشی
Introduction: Climate change is recognized as one of the most critical environmental challenges of the 21st century, significantly impacting ecosystems, natural resources, and human livelihoods.
Behzad Rayegani, Susan Barati, Mohammadrezad Farzaneh, Farhad Hosseini Tayefeh, Abed Torabinia   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Non-uniformly continuous nearest point maps

Proceedings of the American Mathematical Society
We construct a Banach space satisfying that the nearest point map (also called proximity mapping or metric projection) onto any non-singleton compact and convex subset is continuous but not uniformly continuous. The space we construct is locally uniformly convex, which ensures the continuity of all these nearest point maps.
Medina Sabino, Rubén, Quilis, Andrés
openaire   +4 more sources

STRONG CONVERGENCE FOR THREE CLASSES OF UNIFORMLY EQUI-CONTINUOUS AND ASYMPTOTICALLY QUASI-NONEXPANSIVE MAPPINGS [PDF]

Journal of the Korean Mathematical Society, 2008
In this paper, we introduce a modified three-step iteration scheme with errors for three classes of uniformly equi-continuous and asymptotically quasi-nonexpansive mappings in the framework of uniformly convex Banach spaces. We then use this scheme to approximate a common fixed point of these mappings.
Xiaolong Qin, Yongfu Su, Meijuan Shang
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

On ω-Limit Sets of Zadeh’s Extension of Nonautonomous Discrete Systems on an Interval

Mathematics, 2019
Let I = [ 0 , 1 ] and f n be a sequence of continuous self-maps on I which converge uniformly to a self-map f on I. Denote by F ( I ) the set of fuzzy numbers on I, and denote by ( F ( I ) , f ^ ) and ( F ( I ) ,
Guangwang Su, Taixiang Sun
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source