Results 11 to 20 of about 16,770 (217)

A Multivalued Variational Inequality with Unilateral Constraints [PDF]

, 2016
The present paper represents a continuation of [3]. There, we studied a new class of variational inequalities involving a pseudomonotone univalued operator and a multivalued operator, for which we obtained an existence result, among others. In the current paper we prove that this result remains valid under significantly weaker assumption on the ...
Piotr Kalita, Stanislaw Migórski, Mircea Sofonea   +2 more
openaire   +1 more source

Nonlinear periodic system with unilateral constraints

Topological Methods in Nonlinear Analysis, 2019
In this paper, the following periodic system is studied: \[ a(u'(t))' \in A(u(t)) + f(t,u(t),u'(t)) \quad \text{a.e.}\;\, t \in [0,b],\qquad u(0)=u(b), \ u'(0)=u'(b), \] where \(a : \mathbb{R}^N \to \mathbb{R}^N\) is continuous and strictly monotone, \(A\) is a maximal monotone operator with \(D(A) \subset \mathbb{R}^N\), and the map \(f\) is a ...
Sergiu Aizicovici, Nikolaos S. Papageorgiou, Vasile Staicu   +2 more
openaire   +4 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Buckling versus unilateral constraint for a multistable metamaterial element

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2022
A structural element is designed and investigated, forming the basis for the development of an elastic multistable metamaterial. The leitmotif of the structural design is the implementation of a strut characterized by a bifurcation occurring at either vanishing tensile or compressive load.
Hima, N, Bigoni, D, Dal Corso, F
openaire   +5 more sources

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

NonlinearH∞-control under unilateral constraints [PDF]

International Journal of Control, 2016
The primary concern of the work is robust control of hybrid mechanical systems under unilateral constraints of co-dimension one. Nonlinear H∞ output feedback synthesis is developed in the hybrid setting, covering collision phenomena. Robustness issues of the proposed synthesis are numerically illustrated in two benchmark applications.
Montano, Oscar, Orlov, Yury, Aoustin, Yannick   +2 more
openaire   +2 more sources

A Portable Soft Robotic Glove with Fully Functional Thumb Assistance for Complex Dexterous Fine Motor Skills

Advanced Science, EarlyView.
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie, Zhen Wang, Zhongping Ye, Minghao Liu, Xiangqian Shi, Shuk Fan Tong, Jianbin Liu, Chuanbin Mao, Thomas W. Leung, Haitao Liu, Raymond Kai‐yu Tong   +10 more
wiley   +1 more source