Results 121 to 130 of about 1,346,759 (285)

Unilateral acute posterior multifocal placoid pigment epitheliopathy (APMPPE) with delayed contralateral eye involvement

BMC Ophthalmology
Background Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare presumed inflammatory chorioretinopathy characterized by creamy, yellow-white placoid lesions at the level of the retinal pigment epithelium (RPE).
Emanuel Mordechaev, Gabriel Shakarov, Deep Parikh   +2 more
doaj   +1 more source

Case of Unilateral Linear Lichen Planus with Bilateral Mucosal Involvement

Journal of Primary Care Specialties
A form of lichen planus (LP) which follows the Blaschkos line pattern known as linear LP, presents with lichenoid eruptions and violaceous papules in a linear distribution. It is a rare form of LP affecting
Adarshlata Singh, Kaveri Rusia, Drishti Bhatt, Ambika Kondalkar, Bhushan Madke   +4 more
doaj   +1 more source

Unilateral choroidal involvement revealing an acute leukemia

Digital Journal of Ophthalmology
A 56-year-old man presented with unilateral subacute visual loss secondary to an exudative serous retinal detachment of the left eye. The clinical course was later complicated by choroidal thickening and uveal effusion. Laboratory investigations revealed acute myeloid leukemia. Systemic chemotherapy was initiated, resulting in regression of the initial
Soundouss Sebbata, Taoufik Abdellaoui, Soufiane Laksir, Soukaina Laaouina, Houda Brarou, Yassine Mouzari   +5 more
openaire   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Beyond the Marrow: Unilateral Breast Involvement in Acute Lymphoblastic Leukemia

Current Research in MRI
Hematological malignancies involving the breast are exceedingly rare, accounting for less than 1% of all breast tumors. Breast infiltration by acute lymphoblastic leukemia (ALL) is particularly uncommon, with fewer than 25 cases reported in the ...
Ahmet Tuğrul Akkuş, Fadime Güven, Sare Sipal   +2 more
doaj   +1 more source

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Lenz microphthalmic syndrome in an Indian patient

Indian Journal of Ophthalmology, 2007
A case of Lenz microphthalmia syndrome in a seven-month-old male child having features of unilateral anophthalmia, microcephaly, external ear and finger abnormalities, hydrocele and hypospadias is being reported.
Gupta Arvind, Srinivasan Renuka, Pandian Datta, Babu K   +3 more
doaj  

Unilateral retinitis pigmentosa in Von Recklinghausen disease: A rare occurrence

Indian Journal of Ophthalmology. Case Reports
Retinitis pigmentosa (RP) is hereditary progressive retinal dystrophy causing symmetrical affliction of both eyes. Neurofibromatosis 1 (NF1)/Von Recklinghausen disease is a hereditary neurocutaneous disorder with ocular involvement.
Kavin Bhogar, Taru Dewan, Kumari Ritu, Ishita Tyagi   +3 more
doaj   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source