Results 101 to 110 of about 101,596 (292)

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Clinical experience in treatment of diffuse unilateral subretinal neuroretinitis

, 2015
Nidhi Relhan,1,2 Avinash Pathengay,2,3 Vishal Raval,2 Sameera Nayak,2 Himadri Choudhury,3 Harry W Flynn Jr11Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 2Kode Venkatadri Chowdry ...
Nayak S, Relhan N, Choudhury H, Raval V, Flynn HW Jr, Pathengay A   +5 more
core  

Unilateral thalamic edema in internal cerebral venous thrombosis: is it mostly left?

, 2001
Thrombotic occlusion of the internal cerebral veins is a particularly dangerous form of cerebral venous thrombosis (CVT) as it causes venous infarction of the thalami.
Block, Frank, Küker, W., Friese, S, Schmidt, F, Weller, M, Küker, W, Block, F, Friese, S., Weller, M., Schmidt, H.   +9 more
core   +1 more source

Allergic Fungal Sinusitis With Unilateral Eye Involvement [PDF]

Archives of Ophthalmology, 2004
Blake N, Geren, Harry H, Brown, H Graves, Hearnsberger, Christopher T, Westfall   +3 more
openaire   +2 more sources

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

The prognostic value of portal vein and hepatic artery involvement in patients with perihilar cholangiocarcinoma

, 2018
Background: Although several classifications of perihilar cholangiocarcinoma (PHC) include vascular involvement, its prognostic value has not been investigated.
van Vugt, Jeroen L. A., Besselink, Marc G., Ijzermans, Jan N. M., Vugts, Jaynee, Gaspersz, Marcia P., Nio, Chung Y., van Gulik, Thomas M., Busch, Olivier R. C., Labeur, Tim A., Willemssen, François E. J. A., Groot Koerkamp, Bas, Polak, Wojciech G., Coelen, Robert J. S., de Jonge, Jeroen   +13 more
core   +1 more source

The Natural History of Charcot Neuroarthropathy

Foot & Ankle Orthopaedics, 2016
Category: Diabetes Introduction/Purpose: There are limited data in the literature regarding natural history of Charcot Neuroarthropathy (CN) of the foot and ankle.
Justin M. Kane MD, James W. Brodsky MD, Yahya Daoud MS, Alexander Rabinovich MD, FRCS(C)   +3 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Pattern Visual Evoked Potentials in the Fellow Eye of Patients with Unilateral Non-Arteritic Anterior Ischemic Optic Neuropathy

, 2014
Objectives: To compare the results of pattern reversal visual evoked potentials (VEP) in the fellow eye of patients with unilateral nonarteritic anterior ischemic optic neuropathy (NAION) and in the eyes of age-and sex-matched healthy control group ...
Emine Kaya, Elif Demirkılınç Biler, Önder Üretmen, Filiz Afrashi   +3 more
core   +1 more source