Results 21 to 30 of about 294,442 (274)

Comprehensive Genetic Characterization of Four Novel HIV-1 Circulating Recombinant Forms (CRF129_56G, CRF130_A1B, CRF131_A1B, and CRF138_cpx): Insights from Molecular Epidemiology in Cyprus

Viruses, 2023
Molecular investigations of the HIV-1 pol region (2253–5250 in the HXB2 genome) were conducted on sequences obtained from 331 individuals infected with HIV-1 in Cyprus between 2017 and 2021.
Cicek Topcu, Vasilis Georgiou, Johana Hezka Rodosthenous, Georgios Siakallis, Elena Katerina Gavala, Christiana Reveka Dimitriou, Evgenia Zeniou, Brian Thomas Foley, Leondios G. Kostrikis   +8 more
doaj   +1 more source

Emergence of unique recombinant forms (URFs) in Indian HIV-1 epidemic: data from nationwide clinical cohort between 2007 and 2011 [PDF]

Retrovirology, 2012
Neogi U, Gupta S, Shet A, De Costa A, Laishram RL, Wanchu A, Diwan V, Banerjea AC, Sonnerborg A   +8 more
doaj   +2 more sources

Multiple CRF01_AE/CRF07_BC Recombinants Enhanced the HIV-1 Epidemic Complexity Among MSM in Shenyang City, Northeast China

Frontiers in Microbiology, 2022
The transmission of Unique Recombinant Forms (URFs) has complicated the molecular epidemic of HIV-1. This increasing genetic diversity has implications for prevention surveillance, diagnosis, and vaccine design.
Shan He, Shan He, Shan He, Wei Song, Gang Guo, Qiang Li, Minghui An, Minghui An, Minghui An, Bin Zhao, Bin Zhao, Bin Zhao, Yang Gao, Yang Gao, Yang Gao, Wen Tian, Wen Tian, Wen Tian, Lin Wang, Lin Wang, Lin Wang, Hong Shang, Hong Shang, Hong Shang, Xiaoxu Han, Xiaoxu Han, Xiaoxu Han   +26 more
doaj   +1 more source

Characterization of a novel HIV-1 circulating recombinant form, CRF91_cpx, comprising CRF02_AG, G, J, and U, mostly among men who have sex with men

Virulence, 2022
Prospective molecular studies of HIV-1 pol region (2253–5250 in HXB2 genome) sequences from sequenced samples of 269 HIV-1-infected patients in Cyprus (2017–2021) revealed a transmission cluster of 14 unknown HIV-1 recombinants that were not classified ...
Cicek Topcu, Vasilis Georgiou, Johana Hezka Rodosthenous, Ioannis Demetriades, Brian Thomas Foley, Leondios G. Kostrikis   +5 more
doaj   +1 more source

Molecular Epidemiology of HIV-1 in Eastern Europe and Russia

Viruses, 2022
The HIV epidemic in Eastern Europe and Russia is large and not well-controlled. To describe the more recent molecular epidemiology of HIV-1, transmitted drug resistance, and the relationship between the epidemics in this region, we sequenced the protease
Maarten A. A. van de Klundert, Anastasiia Antonova, Giulia Di Teodoro, Rafael Ceña Diez, Nikoloz Chkhartishvili, Eva Heger, Anna Kuznetsova, Aleksey Lebedev, Aswathy Narayanan, Ekaterina Ozhmegova, Alexander Pronin, Andrey Shemshura, Alexandr Tumanov, Nico Pfeifer, Rolf Kaiser, Francesco Saladini, Maurizio Zazzi, Francesca Incardona, Marina Bobkova, Anders Sönnerborg   +19 more
doaj   +1 more source

Origin and Evolution of the Unique Hepatitis C Virus Circulating Recombinant Form 2k/1b [PDF]

Journal of Virology, 2012
ABSTRACTSince its initial identification in St. Petersburg, Russia, the recombinant hepatitis C virus (HCV) 2k/1b has been isolated from several countries throughout Eurasia. The 2k/1b strain is the only recombinant HCV to have spread widely, raising questions about the epidemiological background in which it first appeared.
Raghwani, J, Thomas, X, Koekkoek, S, Schinkel, J, Molenkamp, R, van de Laar, T, Takebe, Y, Tanaka, Y, Mizokami, M, Rambaut, A, Pybus, O   +10 more
openaire   +5 more sources

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill, Ansari AA, Atvinder K. Rullay, Bertozzi CR, Blanch EW, Borchelt D, Caughey B, Caughey B, Caughey B, Caughey BW, Critchley P, David H. Crout, Eberl H, Ferris A, Georges C, Gill AC, Govaerts C, Haire LF, Harris DA, Hornemann S, Ian D. Sylvester, Imanpreet K. Bath, Kazlauskaite J, Kazlauskaite J, Kenyon GL, King SA, Kirby L, Klein TR, Kocienski PJ, Legname G, Matthew R. Hicks, Mui B, Nosjean O, Pan KM, Poss AJ, Safar J, Seddon AM, Shyng SL, Stahl N, Stahl N, Teresa J. T. Pinheiro, Whitesell JK, Wuthrich K, Zahn R, Zhang ZY   +44 more
core   +1 more source

Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits [PDF]

, 2007
The collagen prolyl 4-hydroxylases (P4Hs) are essential for proper extracellular matrix formation in multicellular organisms. The vertebrate enzymes are α2β2 tetramers, in which the β subunits are identical to protein disulfide ...
Abrams, Alan D. Winter, Annunen, Annunen, Annunen, Antony P. Page, Bessereau, Crossen, D'Andrea, Friedman, Gillian McCormack, Helaakoski, Hieta, Hill, Johanna Myllyharju, John, Katriina Keskiaho, Kivirikko, Kivirikko, Kukkola, Lamberg, Liisa Kukkola, Marie-Anne Felix, Merriweather, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Nissi, Page, Pekkala, Quevillon, Riihimaa, Stein, Sulston, Thein, Van den Diepstraten, Veijola, Veijola, Vuori, Williams, Winter, Winter   +44 more
core   +1 more source

Current HIV type 1 molecular epidemiology profile and identification of unique recombinant forms in Jakarta, Indonesia. [PDF]

AIDS Res Hum Retroviruses, 2009
HIV infection is a major problem in Indonesia. The number of people living with HIV has been increasing from year to year, especially among injecting drug users (IDUs). Since there were only limited data about molecular epidemiology profiles of HIV/AIDS in Indonesia, a cross-sectional study involving 208 HIV-1-seropositive individuals was conducted in ...
Sahbandar IN, Takahashi K, Djoerban Z, Firmansyah I, Naganawa S, Motomura K, Sato H, Kitamura K, Pohan HT, Sato S.   +9 more
europepmc   +4 more sources

Circulation of Multiple Patterns of Unique Recombinant Forms B/CRF02_AG in France [PDF]

AIDS, 2011
HIV-1 group M is characterized by substantial genetic diversity, and includes nine subtypes, more than 45 circulating recombinant forms (CRFs), and numerous unique recombinant forms (URFs). In France, the epidemic is characterized by predominance of subtype B strains, increasing prevalence of non-B subtypes (CRF02_AG being the most prevalent) and ...
Leoz, M, Chaix, M, Delaugerre, C., Rivoisy, C, Meyer, L, Rouzioux, C, Simon, F, Plantier, J   +7 more
openaire   +4 more sources