Results 51 to 60 of about 1,145 (256)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Unique solvability of nonlinear Fuchsian equations

Proceedings of the Japan Academy, Series A, Mathematical Sciences, 1989
The unique solvability of a nonlinear Fuchsian equation of the form \[ F(x,y,p_{\alpha \beta}(\partial)\pi x^{\alpha}D^{\beta}_ yu;m_{\alpha \beta}+| \beta | \leq 0)=0; \] is proved under generalized Poincaré conditions.
Madi, Nour Said, Yoshino, Masafumi
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

An internal boundary value problem with the Riemann-Liouville operator for the mixed type equation of the third order

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
The unique solvability of the internal boundary value problem is investigated for the mixed type equation of the third order with Riemann-Liouville operators in boundary condition.
Oleg A Repin, Svetlana K Kumykova
doaj   +1 more source

BOUNDARY-VALUE PROBLEMS WITH GENERALIZED GLUING CONDITIONS FOR A LOADED DIFFERENTIAL EQUATION WITH A PARABOLIC-HYPERBOLIC OPERATOR [PDF]

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2016
In the present work we study the unique solvability of local boundary value problems with generalized gluing conditions for the third order differential equation with a loaded parabolic-hyperbolic operator.
Islomov B., Baltaeva U. I.
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Measure Functional Differential Equations in the Space of Functions of Bounded Variation

Abstract and Applied Analysis, 2013
We establish general conditions for the unique solvability of nonlinear measure functional differential equations in terms of properties of suitable linear majorants.
S. M. Afonso, A. Rontó
doaj   +1 more source

Inverse problem for semilinear Eidelman type equation

Математичні Студії, 2020
The inverse problem for semilinear Eidelman type equation with unknown time dependent function in its right-hand side is considered in this paper. The initial, boundary and integral type overdetermination conditions are posed.
N.P. Protsakh, O. E. Parasiuk-Zasun
doaj   +1 more source

Unique Solvability of an Ordinary Free Boundary Problem

Rocky Mountain Journal of Mathematics, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Unique solvability of the strong Hamburger moment problem [PDF]

Journal of the Australian Mathematical Society. Series A. Pure Mathematics and Statistics, 1986
AbstractMethods from the theory of orthogonal polynomials are extended to L-polynomials . By this means the authors and W. B. Jones (J. Math. Anal. Appl. 98 (1984), 528–554) solved the strong Hamburger moment problem, that is, given a double sequence , to find a distribution function ψ(t), non-decreasing, with an infinitenumber of points of increase ...
Njåstad, Olav, Thron, W. J.
openaire   +2 more sources