Results 131 to 140 of about 2,806,755 (370)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Continued Fractions and Unique Additive Partitions [PDF]

open access: yesarXiv, 1997
A partition of the positive integers into sets $A$ and $B$ {\em avoids} a set $S\subset\N$ if no two distinct elements in the same part have a sum in $S$. If the partition is unique, $S$ is {\em uniquely avoidable.} For any irrational $\alpha>1$, Chow and Long constructed a partition which avoids the numerators of all convergents to $\alpha$, and ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Uniquely 2-List Colorable Graphs [PDF]

open access: yesDiscrete Appl. Math. 119 (2002), no. 3, 217--225, 1999
A graph is called to be uniquely list colorable, if it admits a list assignment which induces a unique list coloring. We study uniquely list colorable graphs with a restriction on the number of colors used. In this way we generalize a theorem which characterizes uniquely 2-list colorable graphs.
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Multi-term fractional differential equations with nonlocal boundary conditions

open access: yesOpen Mathematics, 2018
We introduce and study a new kind of nonlocal boundary value problems of multi-term fractional differential equations. The existence and uniqueness results for the given problem are obtained by applying standard fixed point theorems.
Ahmad Bashir   +3 more
doaj   +1 more source

Uniqueness in Law for Stochastic Boundary Value Problems [PDF]

open access: yesarXiv, 2009
We study existence and uniqueness of solutions for second order ordinary stochastic differential equations with Dirichlet boundary conditions on a given interval. In the first part of the paper we provide sufficient conditions to ensure pathwise uniqueness, extending some known results.
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

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