Results 121 to 130 of about 33,565 (252)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Trafalgar Square, Bridgetown, Barbados

open access: yes, 2018
Landscape, black & white, 4 x 6 in.People can be seen in this area of Barbados, Trafalgar Square, Looking towards St. Michael's Row, Bridgetown. Some can also be seen sitting in the upper seating accommodation located at the left hand side of the square.
Knight &, Co.
core  

A Common Misconception Concerning the "Greater Mean Square Rule" [PDF]

open access: yes, 1953
4 pages, 1 article*A Common Misconception Concerning the "Greater Mean Square Rule"* (Robson, D.
Robson, D. S.   +3 more
core  

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

F-Square Geometries for n = 3, 4, 5, and 6 [PDF]

open access: yes, 1976
19 pages, 1 article*F-Square Geometries for n = 3, 4, 5, and 6* (Federer, W. T.; Lee, F. C.; Mandeli, J.
Mandeli, J. P.   +5 more
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SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

On Embedding a Mateless Latin Square in a Complete Set of Orthogonal F-Squares [PDF]

open access: yes, 1980
This issue was undated. The date given is an estimate.8 pages, 1 article*On Embedding a Mateless Latin Square in a Complete Set of Orthogonal F-Squares* (Mandeli, John P.; Federer, Walter T.) 8 ...
Federer, Walter T.   +4 more
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Unique Set Cover on Unit Disks and Unit Squares

open access: yesCoRR, 2016
We study the Unique Set Cover problem on unit disks and unit squares. For a given set $P$ of $n$ points and a set $D$ of $m$ geometric objects both in the plane, the objective of the Unique Set Cover problem is to select a subset $D'\subseteq D$ of objects such that every point in $P$ is covered by at least one object in $D'$ and the number of points ...
openaire   +2 more sources

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