Results 141 to 150 of about 33,565 (252)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Covering a square of side n+ε with unit squares

, 2006
In [Covering a triangle with triangles, Amer. Math. Monthly 112 (1) (2005) 78; Cover-up, Geombinatorics XIV (1) (2004) 8–9], Conway and I showed that in order to cover an equilateral triangle of side length n+ε, n2+2 unit equilateral triangles suffice ...
Soifer, Alexander
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Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Investigating the relationship between thalamic iron concentration and disease severity in secondary progressive multiple sclerosis using quantitative susceptibility mapping: Cross-sectional analysis from the MS-STAT2 randomised controlled trial

NeuroImage: Reports
Background: Deep grey matter pathology is a key driver of disability worsening in people with multiple sclerosis. Quantitative susceptibility mapping (QSM) is an advanced magnetic resonance imaging (MRI) technique which quantifies local magnetic ...
Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David MacManus, Francesco Grussu, Anita Karsa, Becky Samson, Marco Battiston, Claudia A.M. Gandini Wheeler-Kingshott, Karin Shmueli, Olga Ciccarelli, Frederik Barkhof, Jeremy Chataway, Jeremy Chataway, Thomas Williams, Nevin John, Floriana De Angelis, Alberto Calvi, Alessia Bianchi, Sarah Wright, Madiha Shatila, Anisha Doshi, Wallace Brownlee, Claudia AM. Gandini Wheeler-Kingshott, Frederik Barkhof, Olga Ciccarelli, Jonathan Stutters, Ferran Prados Carrasco, Antonio Ricciardi, Marios Yiannakas, David MacManus, Megan Wynne, Marie Braisher, James Blackstone, Leanne Hockey, Josephine Parker, Jennifer Flight, Chris Frost, Jennifer Nicholas, Stuart Nixon, Judy Beveridge   +50 more
doaj   +1 more source

The dispersion of the Hammersley Sequence in the unit square

Monatshefte f�r Mathematik, 1982
The notion of dispersion, a measure of denseness of sequences, plays an important role in quasi-Monte Carlo optimization. In this paper, we obtain an explicit formula for the dispersion of an important low dispersion sequence, namely the Hammersley Sequence in the unit square.
openaire   +2 more sources

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Paramedics next to ambulance at ceremony

, 1976
A black and white photograph of the dedication ceremony of the Wilmington Paramedic Service at Rodney Square shows two uniformed paramedics and a woman standing next to an ambulance on display with the doors open.
New Castle County Paramedic Unit
core   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Crowd looking inside ambulance

, 1976
A black-and-white photograph of the dedication ceremony for the Wilmington Paramedic Service at Rodney Square shows a crowd of people and paramedics in uniform.
New Castle County Paramedic Unit
core   +1 more source

Breaking trend panel unit root tests [PDF]

This paper proposes Lagrange Multiplier based panel unit root tests allowing for structural breaks through simple extensions of existing group mean and combination tests. The proposed tests are more general than those previously suggested.
Pui Sun Tam, University of Macau
core