Results 41 to 50 of about 11,432,263 (339)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Public Management of Big Data: Historical Lessons from the 1940s

open access: yesFederal History, 2015
This article examines the use of Census Bureau data in 1942 to remove Japanese Americans to internment camps for the duration of World War II. Census data constituted the largest collection of data on Americans at that time.
Margo Anderson
doaj  

Large, Persistent Epidemic of Adenovirus Type 4-Associated Acute Respiratory Disease in U.S. Army Trainees

open access: yesEmerging Infectious Diseases, 1999
In May 1997, a large, persistent epidemic of adenovirus type 4-associated acute respiratory disease began at Fort Jackson, South Carolina, the largest army basic training center. The epidemic lasted until December and declined when vaccine administration
K. Mills McNeill   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The National Nanotechnology Initiative Approach to Environment, Health, and Safety: A Model for Future Science Investments

open access: yesFederal History, 2016
This article discusses the very recent story about the new science of nanotechnology and the careful and clear-headed efforts to regulate it. Nanotechnology offers great promise in numerous applications, including national security, but can also raise ...
Brandi L. Schottel, Barbara Karn
doaj  

Women’s Employment During the Recovery [PDF]

open access: yes, 2011
[Excerpt] In 2010, women represented 46.7 percent of the United States labor force, a slightly larger share than at the start of the recession in 2007. Overall 71.9 million women were employed or looking for work, representing 58.6 percent of all women ...
United States Department of Labor
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

The American People and the New Deal

open access: yesFederal History, 2009
Analysis of the Popular Front created by Franklin Roosevelt during the New Deal in which he was able to appeal to a broad spectrum of society across class, socioeconomic, religious, and political lines.
Michael Kazan
doaj  

Creutzfeldt-Jakob Disease in the United States, 1979-1994: Using National Mortality Data to Assess the Possible Occurrence of Variant Cases

open access: yesEmerging Infectious Diseases, 1996
After a cluster of Creutzfeldt-Jakob disease (CJD) cases among unusually young patients was reported recently from the United Kingdom, we examined trends and the current incidence of CJD in the United States. We found that the age-adjusted CJD death rate
Robert C. Holman   +3 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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