Results 61 to 70 of about 4,424,207 (254)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Farmers' bulletin (United States. Dept. of Agriculture)

open access: yes, 1926
Describes the uses of red clover for forage and as a soil-improving crop in the northeastern United States.
Pieters, A. J.   +1 more
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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Farmers' bulletin (United States. Dept. of Agriculture); no. 1028 (rev.)

open access: yes, 1981
Revised edition. "Strawberries are an important crop in the eastern United States. This bulletin recommends growing methods for that part of the East bounded by the Great Plains on the west and by the Coastal Plain on the south." -- p. 2.
United States. Science and Education Administration.
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

National Cyber Strategy of the United States of America

open access: yes, 2018
With the release of this National Cyber Strategy, the United States now has its first fully articulated cyber strategy in 15 years. This strategy explains how the US will: Defend the homeland by protecting networks, systems, functions, and data; Promote ...
United States. White House Office.
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The United States Marines

open access: yes, 1945
Front: Text describes American advancement and control of Korean and Japanese cities after Japan's formal surrender on 1 Sept., United States time Map shows Japan and Korea. Photographs: Gen.
[United States.] Army Service Forces. Army Information Branch.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Budget of the United States Government.

open access: yes, 1971
Title varies slightly.Purchase from: U.S. Govt. Print. Off., Supt. of Docs., Washington, DC 20402-9328.Report covers fiscal year; fiscal year 1995 in 3 vols.Budget for issued in 2 parts; the second part is labelled "Supplement."Mode of access: Internet ...
United States. Office of Management and Budget.
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