Results 41 to 50 of about 4,424,207 (254)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Leaflet (United States. Department of Agriculture)

open access: yes, 1940
Describes how using mulch can prevent erosion and enable new plant growth on eroded farm field borders in the southeastern United ...
Franklin, Sydney   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

United States 1957;

open access: yes, 1957
Ed. of 1956Includes graphs.
United States. Bureau of the Census. Geography Division;   +1 more
core  

Bats of the United States [PDF]

open access: yesPublic Health Reports (1896-1970), 1954
not possible to generalize with the singular and it is seldom possible with the plural. It can be truthfully stated that bats fly, but there ends the one characteristic that applies to all bats. Their manner of flight, habitat, migration, hibernation, breeding habits, and food preferences are as varied as similar activities among other mammals, for ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

United States Bureau of Mines Bulletin 486

open access: yes, 1951
Report published by the U.S. Bureau of Mines containing the results of a survey of the natural gas resources available in the United States. From the summary:"The Results of a Bureau of Mines survey of helium resources are given in this report and ...
Anderson, C. C.   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Farmers' bulletin (United States. Dept. of Agriculture) ; no. 2157 (rev.)

open access: yes, 1973
Revised edition. This bulletin discusses the cultivation of muscadine grapes in the southern United States. Topics discussed include propagation, pruning and training, soil management, fertilizers, harvesting, common diseases, and ...
United States. Agricultural Research Service. Northeastern Region.
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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