Results 11 to 20 of about 787,943 (334)

Unapproved drugs in the united states and the food and drug administration [PDF]

open access: yesAdvances in Therapy, 2011
Despite more than a century of evolving federal legislation, there remain many unapproved drugs on the United States (US) market. This article reviews the history of drug approval in the US, beginning with the landmark Pure Food and Drug Act of 1906, through to the development of the US Food and Drug Administration (FDA).
Nasr, Alexander   +2 more
openaire   +2 more sources

Development of QSAR models to predict blood-brain barrier permeability

open access: yesFrontiers in Pharmacology, 2022
Assessing drug permeability across the blood-brain barrier (BBB) is important when evaluating the abuse potential of new pharmaceuticals as well as developing novel therapeutics that target central nervous system disorders.
Sadegh Faramarzi   +5 more
doaj   +1 more source

Changes in the genomes and methylomes of three Salmonella enterica serovars after long-term storage in ground black pepper

open access: yesFrontiers in Microbiology, 2022
Low moisture foods (LMFs) have traditionally been recognized as safe for consumption, as most bacteria require higher water content to grow. However, outbreaks due to LMF foods are increasing, and the microbial pathogen Salmonella enterica is frequently ...
Cary P. Davies   +7 more
doaj   +1 more source

Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]

open access: yes, 2012
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed   +3 more
core   +2 more sources

High-Resolution Microbiome Profiling for Detection and Tracking of Salmonella enterica

open access: yesFrontiers in Microbiology, 2017
16S rRNA community profiling continues to be a useful tool to study microbiome composition and dynamics, in part due to advances in next generation sequencing technology that translate into reductions in cost.
Christopher J. Grim   +5 more
doaj   +1 more source

Aging-Induced Dysbiosis of Gut Microbiota as a Risk Factor for Increased Listeria monocytogenes Infection

open access: yesFrontiers in Immunology, 2021
Invasive foodborne Listeria monocytogenes infection causes gastroenteritis, septicemia, meningitis, and chorioamnionitis, and is associated with high case-fatality rates in the elderly.
Mohammad S. Alam   +4 more
doaj   +1 more source

Is Simpler Always Better? Consumer Evaluations of Front-of-Package Nutrition Symbols [PDF]

open access: yes, 2011
Consumers of packaged goods products in the United States recently have faced an onslaught of front-of-package (FOP) nutrition symbols and icons, including the controversial “Smart Choices” single summary indicator.
Andrews, J. Craig   +2 more
core   +3 more sources

Comparative Genomic Characterization of the Highly Persistent and Potentially Virulent Cronobacter sakazakii ST83, CC65 Strain H322 and Other ST83 Strains

open access: yesFrontiers in Microbiology, 2017
Cronobacter (C.) sakazakii is an opportunistic pathogen and has been associated with serious infections with high mortality rates predominantly in pre-term, low-birth weight and/or immune compromised neonates and infants.
Hannah R. Chase   +14 more
doaj   +1 more source

Resolution of the Portunus gladiator species complex: taxonomic status and identity of Monomia gladiator (Fabricius, 1798) and Monomia haanii (Stimpson, 1858) (Brachyura, Decapoda, Portunidae) [PDF]

open access: yesZooKeys, 2019
The United States Food and Drug Administration (FDA) has recently adopted DNA barcoding for the purpose of determining the species identity of commercial seafood products.
Amanda M. Windsor   +2 more
doaj   +3 more sources

Microbiomes Associated With Foods From Plant and Animal Sources

open access: yesFrontiers in Microbiology, 2018
Food microbiome composition impacts food safety and quality. The resident microbiota of many food products is influenced throughout the farm to fork continuum by farming practices, environmental factors, and food manufacturing and processing procedures ...
Karen G. Jarvis   +8 more
doaj   +1 more source

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