Results 11 to 20 of about 478,778 (207)
Machine learning models for rat multigeneration reproductive toxicity prediction
Frontiers in Pharmacology, 2022 Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline ...
Jie Liu +6 more
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Unapproved drugs in the united states and the food and drug administration [PDF]
Advances in Therapy, 2011 Despite more than a century of evolving federal legislation, there remain many unapproved drugs on the United States (US) market. This article reviews the history of drug approval in the US, beginning with the landmark Pure Food and Drug Act of 1906, through to the development of the US Food and Drug Administration (FDA).
Matthew W. Davis +2 more
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The United States Food and Drug Administration and Prescription Drug Promotion [PDF]
Journal of Innovations in Cardiac Rhythm Management, 2019 The impact of prescription drug promotion on health-care professionals (HCPs) is significant. Pharmaceutical industry spending on promotion to HCPs greatly outpaces spending on direct-to-consumer promotion. According to Syneos Health™ PromotionalAnswers, in 2017, the pharmaceutical industry spent more than $24 billion on drug promotion, with more than $
Robert Dean, Ankur S Kalola
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Development of QSAR models to predict blood-brain barrier permeability
Frontiers in Pharmacology, 2022 Assessing drug permeability across the blood-brain barrier (BBB) is important when evaluating the abuse potential of new pharmaceuticals as well as developing novel therapeutics that target central nervous system disorders.
Sadegh Faramarzi +5 more
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Frontiers in Microbiology, 2022 Low moisture foods (LMFs) have traditionally been recognized as safe for consumption, as most bacteria require higher water content to grow. However, outbreaks due to LMF foods are increasing, and the microbial pathogen Salmonella enterica is frequently ...
Cary P. Davies +7 more
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Frontiers in Immunology, 2021 Invasive foodborne Listeria monocytogenes infection causes gastroenteritis, septicemia, meningitis, and chorioamnionitis, and is associated with high case-fatality rates in the elderly.
Mohammad S. Alam +4 more
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High-Resolution Microbiome Profiling for Detection and Tracking of Salmonella enterica
Frontiers in Microbiology, 2017 16S rRNA community profiling continues to be a useful tool to study microbiome composition and dynamics, in part due to advances in next generation sequencing technology that translate into reductions in cost.
Christopher J. Grim +5 more
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Frontiers in Microbiology, 2017 Cronobacter (C.) sakazakii is an opportunistic pathogen and has been associated with serious infections with high mortality rates predominantly in pre-term, low-birth weight and/or immune compromised neonates and infants.
Hannah R. Chase +14 more
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Resolution of the Portunus gladiator species complex: taxonomic status and identity of Monomia gladiator (Fabricius, 1798) and Monomia haanii (Stimpson, 1858) (Brachyura, Decapoda, Portunidae) [PDF]
ZooKeys, 2019 The United States Food and Drug Administration (FDA) has recently adopted DNA barcoding for the purpose of determining the species identity of commercial seafood products.
Amanda M. Windsor +2 more
doaj +3 more sources
Frontiers in Digital Health, 2021 Introduction: The Food and Drug Administration Center for Biologics Evaluation and Research conducts post-market surveillance of biologic products to ensure their safety and effectiveness.
Matthew Deady +9 more
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