Results 141 to 150 of about 777,892 (259)

Hypertension Phenotypes and Mortality Risk in the United States of America: A Data-Driven Cluster Analysis. [PDF]

Int J Hypertens
Carrillo-Larco RM, Varghese JS, Quyyumi A, Narayan KMV, Wilson PWF, Ali MK.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Variability in Insurance Coverage for Adult Voice Therapy in The United States of America. [PDF]

Laryngoscope
Xiao KB, Goldenberg CB, Gates CK, Gilbert MR.   +3 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Developing and assessing acceptability of a shared decision-making tool for selecting among HIV pre-exposure prophylaxis options in the United States of America. [PDF]

PLOS Glob Public Health
Davis WW, Mantsios A, Metzner AA, Talan A, Kwait J, Rodriguez HG, Karver TS, Wilhite D, Barker S, Suarez A, Fernandez R, Rodriguez-Diaz CE, Taggart T, Oglesby A, Wohl D, Barrington C, Kerrigan D.   +16 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The State of Sexual Health in United States of America in 2024: Results from the World Health Organization's Sexual Health Survey (SHAPE). [PDF]

J Sex Marital Ther
Ford JV, Coleman E, de Oliveira L, Rahm-Knigge RL, Mark KP.   +4 more
europepmc   +1 more source

Investigation of Cellular Mechanism through which Salmonella Enterica Serovar Enteritidis Induces Melanoma Cell Death

EJC Skin Cancer
B. Kuran, J. Huang, A. Delano, A. Kartsagoulis, S. Lindahl, C. Ollendike, A. Cartier, S. Okam, R. Hayes, M. Byrne, M. Xian, M. Moreau, Y. Wan   +12 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Evaluation of acid rain in urban areas of the United States of America and Mexico from 2003 to 2019. [PDF]

Environ Monit Assess
Jiménez Alcántara A, Sosa Echeverría R, Gay DA, Alarcón Jiménez AL.   +3 more
europepmc   +1 more source