Results 101 to 110 of about 1,861,870 (345)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The Monument to Freedom and Unity, Berlin: Concerning the Debate about the Need for 'Positive' Monuments in Germany [PDF]

, 2015
Tomáš Vilímek
openalex   +1 more source

Room temperature near unity spin polarization in 2D Van der Waals heterostructures [PDF]

, 2020
Danliang Zhang, Ying Liu, Mai He, Ao Zhang, Shula Chen, Qingjun Tong, Lanyu Huang, Zhiyuan Zhou, Weihao Zheng, Mingxing Chen, Kai Braun, Alfred J. Meixner, Xiao Wang, Anlian Pan   +13 more
openalex   +1 more source

Educating Through Social Media: A Communication Strategy in Instilling Unity Value [PDF]

, 2022
Puri Bestari Mardani, Maria Febiana Christanti   +1 more
openalex   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Social isolation and loneliness among people living with experience of homelessness: a scoping review

BMC Public Health
Social isolation and loneliness (SIL) are public health challenges that disproportionally affect individuals who experience structural and socio-economic exclusion.
James Lachaud, Ayan A. Yusuf, Faith Maelzer, Melissa Perri, Evie Gogosis, Carolyn Ziegler, Cilia Mejia-Lancheros, Stephen W. Hwang   +7 more
doaj   +1 more source

Sweet syndrome presenting with features of cellulitis shortly after femoral angioplasty

European Journal of Case Reports in Internal Medicine
Neutrophilic dermatosis, or Sweet syndrome, is a cutaneous disorder caused by neutrophilic infiltration in the upper dermis. It has been associated with medications, infections and malignancies but to date it has not been associated with femoral arterial
Qi Wang, John Sinclair, Ayyappa Amaravadi, Onovughe Aroriode   +3 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Google star ratings of Canadian hospitals: a nationwide cross-sectional analysis

BMJ Open Quality
Background Data on patients’ self-reported hospital experience can help guide quality improvement. Traditional patient survey programmes are resource intensive, and results are not always publicly accessible.
Irfan Dhalla, Matthew P Tse, Dhruv Nayyar   +2 more
doaj   +1 more source