Results 71 to 80 of about 27,549 (267)

DSL4DT3D: A Model-Driven Approach for Generating 3-D Visualizations of IoT Digital Twins

IEEE Access
Digital Twins (DT) are increasingly being used across industrial, agricultural, and smart city domains to represent and monitor physical systems through virtual replicas. DT are characterized by bidirectional communication between physical assets and the
Fernando Diaz Cantero, Jose A. Barriga, Julio Dominguez Arjona, Miguel A. Perez-Toledano, Pedro J. Clemente   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Recorrido virtual en tercera Dimensión de la Sede principal en una universidad de Bogotá

Publicaciones e Investigación, 2016
El presente documento tiene como objetivo el diseño de una herramienta en tercera dimensión, que permita a estudiantes y funcionarios de una Universidad ubicada en Bogotá, realizar el recorrido virtual de las instalaciones de su sede principal, a través ...
Yuri Vanessa Nieto Acevedo, José Fernando López Quintero, Claudio Camilo González Clavijo   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Analiza możliwości zastosowania środowiska Unity 3D w tworzeniu symulacji postaci

Journal of Computer Sciences Institute, 2016
Niniejsza praca przedstawia analizę możliwości zastosowania środowiska Unity 3D w kontekście symulacji postaci. Jej celem jest analiza porównawcza procesu animacji postaci w wyżej wymienionym środowisku.
Aleksandra Woźniak, Małgorzata Plechawska-Wójcik   +1 more
doaj   +1 more source

3D Modeling and Reconstruction with Blender and Unity 3D

Calenda, 2015
3D visualisation technologies enable and advance the preservation of and research on all kinds of cultural heritage. Modeling, visualising and animating culturally important objects or sites via 3D technologies allow researchers a more detailed and high-resolution view on their research material.  
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Analysis of performance optimization methods for 3D games in the Unity environment

Journal of Computer Sciences Institute
The paper analyzes methods for optimizing performance in 3D games created in Unity. Based on the literature, the following techniques are discussed: GPU Instancing, Static Batching, Occlusion Culling, Level of Detail (LOD), Unity Jobs, Object Pooling ...
Maciej Potręć, Marcin Badurowicz
doaj   +1 more source