Results 111 to 120 of about 71,038 (298)

Public law, knowledge and explanation: a critique on the facilitative nature of public law analysis. [PDF]

, 2006
The aim of this paper is to examine why public law is able to incorporate political theory but excludes feminist critiques. In order to achieve this goal a form of discourse analysis will be undertaken using epistemological and scientific perceptions of ...
Mauthe, Barbara
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Profiling the Swallowing Safety and Efficiency of Patients Presenting With Congestive Heart Failure

Laryngoscope Investigative Otolaryngology
Purpose Existing literature on dysphagia in patients with congestive heart failure (CHF) largely relies on patient‐reported outcomes with limited instrumental data.
Sana Smaoui, Alexandra Taran, Sandhya Ganesan, Vanessa Panes, Gabrielle Deveaux, Nicole Bruni, Reeman Marzouqah   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hyman, Ryle, and the Unity of Knowledge [PDF]

In a number of papers and a book over the past thirty years, John Hyman has developed a unified account of knowledge that builds on Gilbert Ryle and Ludwig Wittgenstein's conceptions of knowledge as closely linked to ‘ability’.
Dougherty, Matt
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

[Rezension von: Petrarch and Boccaccio : the unity of knowledge in the pre-modern world / edited by Igor Candido, 2018] [PDF]

, 2021
Bartuschat, Johannes 1966-
core   +1 more source

T.E. Hulme and the problem of unity. [PDF]

, 1963
T. E. Hulme is a controversial figure in modern literary criticism but his influence on the thought of T. S. Eliot and on the principles behind the Imagist movement is assured.
Sanson, Barbara Anne
core  

Bias in machine learning applications to address non-communicable diseases at a population-level: a scoping review

BMC Public Health
Background Machine learning (ML) is increasingly used in population and public health to support epidemiological studies, surveillance, and evaluation.
Sharon Birdi, Roxana Rabet, Steve Durant, Atushi Patel, Tina Vosoughi, Mahek Shergill, Christy Costanian, Carolyn P. Ziegler, Shehzad Ali, David Buckeridge, Marzyeh Ghassemi, Jennifer Gibson, Ava John-Baptiste, Jillian Macklin, Melissa McCradden, Kwame McKenzie, Sharmistha Mishra, Parisa Naraei, Akwasi Owusu-Bempah, Laura Rosella, James Shaw, Ross Upshur, Andrew D. Pinto   +22 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source