Results 91 to 100 of about 5,418,138 (286)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Chaos, Solitons & Fractals, 2005 Several corrections of typos and smaller revisions, final ...
openaire +4 more sources
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
The local and the universal in Ecuadorian art applied to architectural education
ESTOA: Revista de la Facultad de Arquitectura y Urbanismo de la Universidad de CuencaThe relationship between the local and the universal in creative processes is examined, using the methodology of Architectural and Urban Design I Workshop from the Architecture program at Pontificia Universidad Católica del Ecuador (PUCE) during 2022 ...
Javier Benavides-Alvarez +1 more
doaj +1 more source
Fundamenta Mathematicae, 2014 A function of two variables F(x,y)is universal iff for every other function G(x,y) there exists functions h(x) and k(y) with G(x,y) = F(h(x),k(y)) Sierpinski showed that assuming the continuum hypothesis there exists a Borel function F(x,y) which is universal. Assuming Martin's Axiom there is a universal function of Baire class 2.
Larson, Paul B. +3 more
openaire +2 more sources
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
Marcelle Delpastre (1925-1998). Relégation au local et aspiration à l’universel
Les Dossiers du GRIHL, 2008 Marcelle Delpastre (1925-1998) spent her whole life on a farm in the Correze. While ramining a full-time farmer, she became the author of a wide-ranging and very diverse oeuvre (poetry, novellas, ethnograghic works, mémoires, etc.) in French and Limousin
Jean-Pierre Cavaillé
doaj +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source
i-Perception, 2011 In our previous experiments, it was shown that odors (rose, sandalwood) might influence the haptic perception (stiffness, roughness). In particular, subjects felt a smooth surface even smoother with rose odor and a stiff surface even harder with ...
Yurie Nishino +3 more
doaj +1 more source