Results 51 to 60 of about 1,197,327 (279)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Universality of slip avalanches in flowing granular matter

open access: yesNature Communications, 2016
Whether the deformation of amorphous materials is governed by universal scaling, a characteristic feature of the critical phenomena, is currently under debate. Here, Denisov et al.
D. V. Denisov   +4 more
doaj   +1 more source

Universal adhesives - a new direction in the development of adhesive systems

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2020
Objectives: In the past decade, many new adhesive systems labeled as universal were introduced. Their common characteristic is that they can be applied to hard dental tissues either in self-etch or etch-and-rinse mode, and they are also able to bond to ...
A. Tichý, K. Hosaka, J. Tagami
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

泛灰数学在平面刚体导引连杆机构综合中的应用

open access: yesJixie chuandong, 2002
This paper focuses on the method of solving the non-linear equation arising form the synthesis of plane rigid guidance. Based on the concept of universal Grey number and the rules of four algebraic operation of universal Grey number,it is introduced ...
罗佑新   +3 more
doaj  

Formation of universal learning activities of younger schoolchildren as a pedagogical problem

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2018
Formation of universal learning activities in the system of elementary education as a pedagogical problem is considered. The bases of “universal learning activities” notion are revealed.
Y. P. Prokudin, E. A. Мilenko
doaj   +1 more source

An effective Arakelov-theoretic version of the hyperbolic isogeny theorem

open access: yes, 2015
For an integer $e$ and hyperbolic curve $X$ over $\overline{\mathbb Q}$, Mochizuki showed that there are only finitely many isomorphism classes of hyperbolic curves $Y$ of Euler characteristic $e$ with the same universal cover as $X$.
Javanpeykar, Ariyan
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Topological properties of Wazewski dendrite groups

open access: yes, 2019
Homeomorphism groups of generalized Wa\.zewski dendrites act on the infinite countable set of branch points of the dendrite and thus have a nice Polish topology. In this paper, we study them in the light of this Polish topology.
Duchesne, Bruno
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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