Results 41 to 50 of about 2,160,399 (278)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Beyond the Buzzword: Unpacking ‘Special Needs’ in Denmark

open access: yesScandinavian Journal of Disability Research
The term ‘special needs’ encompasses various definitions of what is considered ‘special’ for children with functional variations. These definitions reflect societal views shaped by politics, economics, governance, and knowledge, all of which ...
Pia Ringø, Emil Søbjerg Falster
doaj   +1 more source

Evaluation of Library Interior Spaces Within the Context of Universal Design Principles: Karadeniz Technical University Faik Ahmet Barutcu Library

open access: yesJournal of Architectural Sciences and Applications, 2021
With the changing and developing conditions, people's expectations from the places have also been affected and the concept of 'accessibility' has gained more importance. Structures whose user is everyone must meet the needs of users.
İrem Bekar
doaj   +1 more source

Designing Cyclic Universe Models [PDF]

open access: yesPhysical Review Letters, 2004
Recent advances in understanding the propagation of perturbations through the transition from big crunch to big bang (esp. Tolley et al. hep-th/0306109) make it possible for the first time to consider the full set of phenomenological constraints on the scalar field potential in cyclic models of the universe.
Khoury, Justin   +2 more
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Analysis of the Application of Universal Design Standards to Interior-Architecture Design [PDF]

open access: yes, 2019
A lot of research shows the findings of cases of public facilities that are not accessible to people with disabilities and see the importance of a design especially in the field of architecture-interior that is able to produce a user-friendly and barrier-
Cardiah, T. (Tita )   +4 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Universal Design Learning (UDL) for Extension Audiences

open access: yesEDIS
Universal Design Learning (UDL) is about designing for the minority in the learning environment to meet the needs of all. This publication explains the principles of Universal Design Learning—engagement, representation, and action and expression—and how
Vanessa Spero
doaj   +1 more source

Zerotree design for image compression: toward weighted universal zerotree coding [PDF]

open access: yes, 1997
We consider the problem of optimal, data-dependent zerotree design for use in weighted universal zerotree codes for image compression. A weighted universal zerotree code (WUZC) is a data compression system that replaces the single, data-independent ...
Effros, Michelle
core   +1 more source

A Theory of Cheap Control in Embodied Systems

open access: yes, 2014
We present a framework for designing cheap control architectures for embodied agents. Our derivation is guided by the classical problem of universal approximation, whereby we explore the possibility of exploiting the agent's embodiment for a new and more
B Sallans   +43 more
core   +5 more sources

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