Results 31 to 40 of about 1,187,117 (281)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

THE IMPLEMENTATION OF GRAMMATICAL FUNCTIONS IN FUNCTIONAL DISCOURSE GRAMMAR [PDF]

open access: yes, 2007
underlying representation in a more or less across the board fashion, only taking into consideration the language dependent semantic function hierarchy.
Bakker, D.   +5 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Categorical Acquisition: Parameter-Setting in Universal Grammar

open access: yesBiolinguistics, 2007
Two triggering models of parameter-setting, the Hierarchical Acquisition model endorsed by Baker (2001, 2005) and Wexler’s (1998) Very Early Parameter Setting model, are compared with Yang’s (2002, 2004) Variational model.
Rosalind Thornton, Graciela Tesan
doaj   +1 more source

The Guides Verbs in the Arabic Language: Are Its Terms Originals or Borrowed?

open access: yesTanwir Arabiyyah, 2021
Grammarists differed about the definition of the verb in the Arabic language, but they were in great agreement in dividing it from different sides. From these sides, we find the division of verbs according to the function of directing, which is the ...
Safi Khadidja
doaj   +1 more source

Universal health plan proposal. Spanish

open access: yes, 2022
Title from PDF caption (viewed on September 14, 2022)."El Grupo de Trabajo Conjunto sobre Atención Universal comenzó con la aprobación de la Ley 770 del Senado.

core  

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

Grammar in Language and Listening Acquisition

open access: yesAna Dili Eğitimi Dergisi, 2023
The existence and self-realization of humans are possible due to language, language faculty, and listening acquisition. Anything animate or inanimate perceived in the external world such as an object, phenomenon, entity, etc.
Ahmet Akkaya, İbrahim Doyumğaç
doaj   +1 more source

Bound person forms in ditransitive clauses revisited. [PDF]

open access: yes, 2007
In a recent article Gensler (2003) has argued that little can be said about the ordering of bound person markers of the T(heme) and R(ecipient) relative to each other or relative to the verb stem apart from the fact that the outer markers are likely to ...
Bakker, D.   +3 more
core   +1 more source

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