Results 21 to 30 of about 220,085 (291)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

ARISTOTLE ON PERCEPTION AND UNIVERSALS: AN EXTENSIONAL READING

Tópicos, 2013
This paper offers an extensional account of Aristotle’s theory of perceptual content. To do so I make use of an extensional account of Aristotle’s notion of universals and related notions.
Eduardo García-Ramírez
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Universales atributivos de la filosofía helénica antigua : Eíde, Tópoi y Lektá [PDF]

, 2012
In this paper we defend that Hellenistic philosophy has created two fundamentals: scientific truths and the physical-rational being. Now, to avoid dogmatisms, they have to be understood as accumulative universals.
Pérez Herranz, Fernando Miguel
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Dependencias Universales para los treebanks AnCora [PDF]

, 2016
The present article describes the conversion of the Catalan and Spanish AnCora treebanks to the Universal Dependencies formalism. We describe the conversion process and assess the quality of the resulting treebank in terms of parsing accuracy by means of
Martínez Alonso, Héctor, Zeman, Daniel
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Espacio modal y universales estructurales máximos

Estudios de Filosofía, 2010
este trabajo considera la viabilidad de la teoría de los mundos posibles como universales estructurales máximos en relación con las conocidas críticas contra concepciones actualistas de los mundos posibles.
José Tomás Alvarado Marambio
doaj  

Racionalismo, empirismo y funcionalismo en la explicación de universales lingüísticos

Revista de Filología y Lingüística de la Universidad de Costa Rica, 2015
El presente artículo consta de dos partes: en la primera se caracteriza el concepto de universal lingüístico desde las perspectivas racionalista (generativismo chomskyano) y empirista (tipologismo greenbergiano) y se reseñan las distinciones: a ...
Carla Victoria Jara Murillo
doaj   +1 more source