Results 61 to 70 of about 1,105,380 (358)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Music: Specialized to Integrate?
Empirical Musicology Review, 2015 In her paper Schaefer (2014) provides a relevant amount of behavioral and neuroimaging evidence within and outside the realm of music favoring the notion that predictive processing plays a prominent role in the coupling of perception, cognition and ...
Paulo Estêvão Andrade +1 more
doaj +1 more source
Moral category of human rights in the country’s defense [PDF]
Војно дело, 2016 Nowadays the world is defined and essentially functions through the idea of law and justice. Human rights are among basic values of modern civilization and are becoming a matter of general concern and international responsibility.
Narančić Mane
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
AxiomsThe famous Riemann hypothesis (RH) asserts that all non-trivial zeros of the Riemann zeta function ζ(s) (zeros different from s=−2m, m∈N) lie on the critical line σ=1/2.
Antanas Laurinčikas
doaj +1 more source
Critical remarks on Religion in the public sphere' – Habermas between Kant and Kierkegaard
Etikk i Praksis: Nordic Journal of Applied Ethics, 2009 This article provides a critical assessment of Habermas's recent work on religion and the role of religion in the public sphere by comparing it to Kant's philosophy of religion on the one hand and that of Kierkegaard on the other.
Roe Fremstedal
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Universality and diversity in human song
, 2018 What is universal about music across human societies, and what varies? We built a corpus of ethnographic text on musical behavior from a representative sample of the world’s societies and a discography of audio recordings of the music itself.
Samuel A. Mehr +18 more
semanticscholar +1 more source
Universal Peptidomimetics [PDF]
Journal of the American Chemical Society, 2010 This paper concerns peptidomimetic scaffolds that can present side chains in conformations resembling those of amino acids in secondary structures without incurring excessive entropic or enthalpic penalties. Compounds of this type are referred to here as minimalist mimics.
Eunhwa, Ko +5 more
openaire +2 more sources