Results 91 to 100 of about 16,264 (308)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Universals in English Platonism: More, Cudworth, Norris
, 2017 The essay reconstructs the topic of universals in the Cambridge Platonists' and John Norris' epistemologies and ontologies. More and Cudworth restrict universals to the mental realm, stating that whatsoever exists without the mind is singular.
LOTTI, Brunello
core +1 more source
Materia i przyczynowość - konkrety czy uniwersalia?
Zagadnienia Filozoficzne w Nauce, 2011 Humean doctrine on causality is well known. Since all our knowledge comes from experience, we are able to know that “B follows A” (B propter A) but not that “B is caused by A” (B propter A). All the rest comes from our mental habits.
Michał Heller
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
COMMUNICATION AND GRAMMATICALIZATION. THE CASE OF (CROATIAN) DEMONSTRATIVES
Fluminensia: Journal for Philological Research, 2015 The focus of this paper is on the role that shared reference plays in communication and, relatedly, on the way in which communicative needs drive the formation and development of grammatical categories.
Maja Brala-Vukanović
doaj
, 2017 Like many prominent early moderns, Spinoza espouses a brand of nominalism about “abstractions and universals,” and he frequently warns against confusing universals with real things. While many of his conclusions about the status and origins of universals
Samuel Newlands
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Adjective Similes as Lexical Universals
Polylinguality and Transcultural Practices, 2019 The article deals with adjective similes of some Slavonic, Baltic and German languages from the position of typology and linguistics of universals and is aimed at revealing common fixed expressions.
Irina A. Muzheika
doaj +1 more source
How “Universal” are Universal Precautions?
AMA Journal of Ethics, 2009 Guidelines to improve observance of universal precaution standards and reporting of needlestick injuries by medical students and resident physicians. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +2 more sources