Results 91 to 100 of about 108,877 (311)

Nominalism [PDF]

open access: yes, 2019
‘Nominalism’ refers to a family of views about what there is. The objects we are familiar with (e.g. hands, laptops, cookies, and trees) can be characterized as concrete and particular. Nominalists agree that there are such things.
Guigon, Ghislain
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Does Ockham’s razor matter to the problem of universals?

open access: yesGriot
This paper investigates how Ockham’s Razor can be applied to compare and evaluate solutions to the Problem of Universals. Initially, I discuss three formulations of this principle.
Valdetonio Pereira de Alencar
doaj   +1 more source

A Formal Theory of Substances, Qualities, and Universals [PDF]

open access: yes, 2004
One of the tasks of ontology in information science is to support the classification of entities according to their kinds and qualities. We hold that to realize this task as far as entities such as material objects are concerned we need to distinguish ...
Grenon, Pierre   +2 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

How “Universal” are Universal Precautions?

open access: yesAMA Journal of Ethics, 2009
Guidelines to improve observance of universal precaution standards and reporting of needlestick injuries by medical students and resident physicians. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire   +2 more sources

Materia i przyczynowość - konkrety czy uniwersalia?

open access: yesZagadnienia Filozoficzne w Nauce, 2011
Humean doctrine on causality is well known. Since all our knowledge comes from experience, we are able to know that “B follows A” (B propter A) but not that “B is caused by A” (B propter A). All the rest comes from our mental habits.
Michał Heller
doaj  

What in the World is Universe? : A Prime Example [PDF]

open access: yesФилософия и космология, 2016
This writing attempts to capture mind and matter to rational description by focusing on disparity between scientific method as it extracts concepts and discards particulars and ordinary cognitive functioning that extends from proximal experience ...
Marvin E. Kirsh
doaj  

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