Results 51 to 60 of about 108,259 (287)
DSRP Theory is now over 25 years old with more empirical evidence supporting it than any other systems thinking framework. Yet, it is often misunderstood and described in ways that are inaccurate.
Derek Cabrera, Laura Cabrera
doaj +1 more source
What Questions Arise when Studying Cultural Universals in Depression? Lessons from Abnormal Psychology Textbooks [PDF]
We examined 70 abnormal psychology textbooks published from 1920s to the present to identify consistent cross-cultural themes with regard to human depressive experiences over time and across regions of the world.
Chang, Robert, Tanaka-Matsumi, Junko
core +3 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Some Introductory Words For Two Little Earth Cousins
This article is an introduction to the subsequent one by Jodi Latremouille's "My Treasured Relation." It demonstrates that hermeneutic work is always about the application of particular cases to universals, demanding of universals to listen to the ...
David W Jardine
doaj +1 more source
Instantiation and Characterization: Problems in Lowe's Four-Category Ontology [PDF]
According to Lowe’s Four-Category Ontology, the general nature of the entities belonging to the four fundamental categories is determined by the basic formal ontological relations (instantiation and characterization) that they bear to other entities.
Keinänen, Markku
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The authors propose that the theoretical framework of Western philosophy is supported by metaphysical ontology through the differentiation and analysis of two different kinds of “particulars-universals” in Plato’s “world visible to the naked eye” and ...
Wei Yan, Xia Wang, Zongrong Li
doaj +1 more source
A Formal Theory of Substances, Qualities, and Universals [PDF]
One of the tasks of ontology in information science is to support the classification of entities according to their kinds and qualities. We hold that to realize this task as far as entities such as material objects are concerned we need to distinguish ...
Grenon, Pierre +2 more
core
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Particularity as Paradigm: A Wittgensteinian Reading of Hegel’s Subjective Logic [PDF]
I provide a distinctively Wittgensteinian interpretation of Hegel’s Subjective Logic, including the parts on the concept, the judgement and the syllogism.
Mácha, Jakub
core +1 more source

