Results 61 to 70 of about 108,877 (311)

DSRP Theory: A Primer

open access: yesSystems, 2022
DSRP Theory is now over 25 years old with more empirical evidence supporting it than any other systems thinking framework. Yet, it is often misunderstood and described in ways that are inaccurate.
Derek Cabrera, Laura Cabrera
doaj   +1 more source

Cultural transmission results in convergence towards colour term universals. [PDF]

open access: yes, 2013
As in biological evolution, multiple forces are involved in cultural evolution. One force is analogous to selection, and acts on differences in the fitness of aspects of culture by influencing who people choose to learn from.
Dowman, Mike, Griffiths, Tom, Xu, Jing
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Universals of Human Nature: A Method of Their Detection through Scientific Evidence and Literary Fiction

open access: yesProfil
With the arrival of biological evolutionism and behaviourism, the concept of human nature has become very unstable. The proposed method for detecting the features of human nature based on discomfort allows us to reconsider human nature and regard the ...
Tomáš Károly
doaj   +1 more source

Motive der Universalienforschung [PDF]

open access: yes, 1977
The search for universals is a tendency which is based in the structure of human knowledge and which correlates with a complementary search for individual properties. The recurrence to universals is inherent in both classificatory and deductive knowledge.
Holenstein, Elmar
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Instantiation and Characterization: Problems in Lowe's Four-Category Ontology [PDF]

open access: yes, 2018
According to Lowe’s Four-Category Ontology, the general nature of the entities belonging to the four fundamental categories is determined by the basic formal ontological relations (instantiation and characterization) that they bear to other entities.
Keinänen, Markku
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A Modest Proposal for Resolving the Apparently Never-Ending Evolution Debate: Reconsidering the Question

open access: yesStudia Gilsoniana, 2019
The author makes an attempt to show why (1) Darwin’s teaching in The Origin of Species by Means of Natural Selection and The Descent of Man and Selection in Relation to Sex cannot be “scientific” in a modern, classical, or any, sense and that ...
Peter A. Redpath
doaj   +1 more source

Derrida's Territorial Knowledge of Justice [PDF]

open access: yes, 2012
Peter Fitzpatrick’s writings prove once and for all that it is possible for a law professor to write in beautiful English. His work also proves once and for all that the dominating tradition of Anglo-American legal philosophy and of law teaching has been
Conklin, William
core  

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