Results 51 to 60 of about 16,264 (308)
Qualia and the Problem of Universals [PDF]
, 2007 In this paper I explore the logical relationship between the question of the reality of qualia and the problem of universals. I argue that nominalism is inconsistent with the existence of qualia, and that realism either implies or makes plausible the ...
Sharlow, Mark
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Inter language and language universals [PDF]
, 1989 The field of interlanguage studies has made significant headway in recent years by seeking to identify the direction and nature of learners' development towards self-perceived target language norms.
Harris, Wiliam J
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Systems, 2022 DSRP Theory is now over 25 years old with more empirical evidence supporting it than any other systems thinking framework. Yet, it is often misunderstood and described in ways that are inaccurate.
Derek Cabrera, Laura Cabrera
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Computer Sciences & Mathematics Forum, 2023 The authors propose that the theoretical framework of Western philosophy is supported by metaphysical ontology through the differentiation and analysis of two different kinds of “particulars-universals” in Plato’s “world visible to the naked eye” and ...
Wei Yan, Xia Wang, Zongrong Li
doaj +1 more source