Results 51 to 60 of about 2,696 (268)

Non-Trivial Universes and Sequences of Universes

open access: yesFormalized Mathematics, 2022
Summary Universe is a concept which is present from the beginning of the creation of the Mizar Mathematical Library (MML) in several forms (Universe, Universe_closure, UNIVERSE) [25], then later as the_universe_of, [33], and recently with the definition GrothendieckUniverse [26], [11], [11].
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

LANGUAGE UNIVERSALS AND UNIVERSAL INPUT CONDITIONS (SIUSANA KWELDJU)

open access: yesGetsempena English Education Journal, 2016
This essay discusses about human language, human have the common system in their language. The same system of the languages is called as Language Universals.
Maulizan ZA
doaj  

Relativity, linguistic variation and language universals

open access: yesCogniTextes, 2010
Language universals are usually thought of as properties holding of all languages. But very few, if any, such universals exist, due to the extreme structural diversity of languages.
William Croft
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Basic Verbs of Possession

open access: yesCogniTextes, 2010
Verbs of possession such as HAVE and GIVE have been extensively studied both typologically and from a cognitive linguistic perspective. The present study presents an analysis of possession verbs as a semantic field with a focus on the most basic verbs ...
Åke Viberg
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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