Results 91 to 100 of about 122,810 (295)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Философия и космология, 2016 This article discusses some of the unsolved problems of modern cosmology, which lead to the need to consider the role of living matter in the evolution of the universe. The author proposes the hy- pothesis of the emergence, in the process of evolution of
Eduard Kazantsev
doaj
Energy–Momentum In The Viscous Kasner-Type Universe In Teleparallel Gravity [PDF]
, 2005 Mustafa Saltı
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Olbers' Paradox and the Background Radiation Density in an Isotropic Homogeneous Universe [PDF]
, 1965 E. R. Harrison
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Comptes Rendus. Mathématique, 2011 In the category of left modules over a unital ring we show that a left exact reflector determines, for each n⩾1, a torsion theoretic setting in which universal extensions of length n exist. Combined with recent work of Rodelo and van der Linden (2011) [9] this establishes the existence of universal central extensions of groups and Lie algebras ...
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
PEDAGOGY OF UNIVERSAL ARTISTIC THOUGHT
Russian Journal of Education and PsychologyBackground. The article examines the phenomenon of artistic and imaginative thinking and its formation in humans as a pedagogical reality. The problem is as important as it is poorly studied in the literature.
Pavel A. Gagaev
doaj +1 more source
Observational constraints on the model parameters of a class of emergent universe [PDF]
, 2012 S. Ghose, P. Thakur, B. C. Paul
openalex +1 more source