Results 21 to 30 of about 932,670 (260)
Estudos de SociologiaO presente trabalho aponta para alguns dos desafios enfrentados pelos Países Africanos de Língua Oficial Portuguesa (PALOPS) na consolidação da Sociologia como área do conhecimento relevante, seja no âmbito universitário ou escolar.
Rodrigo de Souza Pain +1 more
doaj +1 more source
Pro-Posições, 2009 Este artigo é uma reflexão sobre o papel que as universidades paulistas e paranaenses desempenham no processo de formação acadêmica dos estudantes dos Países Africanos de Língua Oficial Portuguesa (Palop), em particular os angolanos.
Dagoberto José Fonseca
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Viso, 2017 Com o ingresso da Viola Caipira na universidade, a possibilidade de um diálogo com a academia pode ser recebida como um período de análises produtivas neste universo.
Sidnei de Oliveira
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Ortega y Gasset: Universidade e Ciência
Revista de Ciências Humanas, 2015 Neste artigo investiga-se como o filósofo espanhol Ortega y Gasset associa os limites da razão científica com a crise de cultura que ele enxerga na Europa.
José Maurício de Carvalho +1 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Avaliação e ranqueamento de universidades sob a lógica de critérios globais
Roteiro, 2018 O mundo globalizado tem provocado diversos impactos no contexto universitário, especificamente a necessidade de adequação das instituições aos novos paradigmas impostos pelas mudanças em todos os setores da sociedade.
Raimunda Maria da Cunha Ribeiro
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source