Results 31 to 40 of about 3,650,943 (307)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Avaliação e ranqueamento de universidades sob a lógica de critérios globais
Roteiro, 2018 O mundo globalizado tem provocado diversos impactos no contexto universitário, especificamente a necessidade de adequação das instituições aos novos paradigmas impostos pelas mudanças em todos os setores da sociedade.
Raimunda Maria da Cunha Ribeiro
doaj +1 more source
Universidad de Alicante, universidad cardioprotegida
, 2017 Introducción: La parada cardíaca (PC) es una patología muy frecuente. En España hay 30.000 muertes súbitas al año y 20.000 intentos de reanimación. Posibilidades de supervivencia de PC secundaria a una arritmia ventricular en la calle: 5-10%.
García Aracil, Noelia +5 more
openaire +2 more sources
Potencialidades do teatro de fantoches na educação rodoviária: uma abordagem no âmbito da educação para a cidadania [PDF]
, 2007 Dissertação de mest., Educação Artística, Faculdade de Ciências Humanas e Sociais, Universidade do Algarve, 2007Ao longo da presente pesquisa – Potencialidades do teatro de fantoches na educação rodoviária: uma abordagem no âmbito da educação para a ...
Estêvão, Sandra Isabel de Brito
core
Analysis of cosmic ray variations observed by the CARPET in association with solar flares in 2011-2012 [PDF]
, 2013 The CARPET cosmic ray detector was installed on April 2006 at CASLEO (Complejo Astronmico El Leoncito) at the Argentinean Andes (31.8S, 69.3W, 2550 m, Rc=9.65 GV).
Bazilevskaya, G. A. +8 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Exploring RNA-targeted gene therapy approaches for hypertrophic cardiomyopathy [PDF]
, 2012 Relatório de projeto no âmbito do Programa de Bolsas Universidade de Lisboa/Fundação Amadeu Dias (2011/2012). Universidade de Lisboa.
Freitas, Ana
core
Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice [PDF]
, 2017 Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs.
Camarini, Rosana +6 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source