Results 41 to 50 of about 3,650,943 (307)

Quantum work for sudden quenches in Gaussian random Hamiltonians [PDF]

, 2018
In the context of nonequilibrium quantum thermodynamics, variables like work behave stochastically. A particular definition of the work probability density function (pdf) for coherent quantum processes allows the verification of the quantum version of ...
Arrais, Eric G., Céleri, Lucas C., De Almeida, Norton G., Roncaglia, Augusto Jose, Toscano, Fabricio, Wisniacki, Diego Ariel   +5 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Dibucaine in Ionic-Gradient Liposomes: Biophysical, Toxicological, and Activity Characterization [PDF]

, 2018
Administration of local anesthetics is one of the most effective pain control techniques for postoperative analgesia. However, anesthetic agents easily diffuse into the injection site, limiting the time of anesthesia. One approach to prolong analgesia is
Alonso, Silvia del Valle, Castro, Simone R., Couto, Verônica M., Dantzger, Darlene D., de Paula, Eneida, Feas, Daniela Agustina, Guilherme, Viviane A., Igartúa, Daniela, Machado, Daisy, Prieto, Maria Jimena, Ribeiro, Lígia N.M., Silva, Camila M.G.   +11 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Lei Pró-Negros, Interpretação Pró-Brancos: racismo institucional, jeitinhos e burlas para a não implementação da Lei n.º 12.990/2014 em universidades federais [PDF]

Sociologias
Resumo O debate aqui proposto sobre a implementação da Lei n.º 12.990/2014 nos concursos para o magistério superior nas universidades federais revela a fragilidade do Ministério Público (MP) na proteção de direitos à população Negra.
Edmilson Santos, Mário Resende, Georgina Nunes   +2 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Universidad

Entretextos, 2011
[ES] Definición del término Universidad en el diccionario Dicter. [EN] Definition of the word Universidad in the dictionary Dicter.
openaire   +3 more sources

LA UNIVERSIDAD NERD [PDF]

Revista chilena de literatura, 2013
Las universidades son, desde el siglo XIII europeo, y desde las postrimerías de la era colonial en América, el reino oficial u oficializado del conocimiento. Fueron mayormente públicas, hoy ya no, y las fronteras que antes había entre lo público y lo privado se han hecho borrosas.
openaire   +3 more sources

Geochemical constraints on the Hadean environment from mineral fingerprints of prokaryotes [PDF]

, 2017
The environmental conditions on the Earth before 4 billion years ago are highly uncertain, largely because of the lack of a substantial rock record from this period.
Abrevaya, Ximena Celeste, Chaffin, Michael S., Conti, Maria Josiane, Navarro, Margareth Sugano, Novoselov, Alexey A., Schneider, Jerusa, Serrano, Paloma, Silva, Dailto, Souza Filho, Carlos Roberto de   +8 more
core   +1 more source