Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Strategies for embedding eLearning in traditional universities: drivers and barriers [PDF]
This paper addresses the question: how can elearning be embedded in traditional universities so that it contributes to the transformation of the university?
Fox, Seamus, MacKeogh, Kay
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Achieving the Dream and Four-Year Institutions: Perspectives from Three Houston Colleges [PDF]
This report examines the experiences of three Houston area four-year universities that are participating in Achieving the Dream, a national initiative designed to use data-driven decision making to promote student success, especially among low-income ...
at Virginia Commonwealth University, The Grace E. Harris Leadership Institute +4 more
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The applicability of performance-based funding mechanisms in Malaysian Public Universities [PDF]
A performance-based funding (PBF) mechanism is now widespread in educational institutions in both developed and developing countries. The Malaysian Government also has intention to implement PBF in public universities, yet no study has explored the ...
Kek, Siok Yee
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Establishment and Verification of the UAV Coupled Rotor Airflow Backward Tilt Angle Controller
At present, all the flight controllers of agricultural UAVs cannot accurately and quickly control the influencing factors of the UAV coupled rotor airflow backward tilt angle during the application process.
Han Wu +9 more
doaj +1 more source
Intermediate Role of the Criterion of Focus on the Students Benefiting in the Relationship between Adopting the Criterion of Partnership and Resources and Achieving Community Satisfaction in the Palestinian Universities [PDF]
The study aimed at identifying the intermediate role of the criterion of emphasis on students and beneficiaries in the relationship between adopting the criterion of partnership and resources and achieving the satisfaction of the society.
Abu-Naser, Samy S. +3 more
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

