Results 131 to 140 of about 6,075,495 (359)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Okanagan Charter : An international charter for health promoting universities & colleges
A new international charter, an outcome of the 2015 International Conference on Health Promoting Universities and Colleges / VII International Congress, signals a challenge to universities and colleges to create healthier campuses and healthier ...
International Conference on Health Promoting Universities & Colleges (7th : 2015 : Kelowna, (B.C.))
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Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Keep it clever: policy statement 2016
Australia is at an economic and productivity crossroads. In an era of sweeping change, other nations are seizing the future with investments in higher education, research, innovation and skills. Australia now faces a stark choice: we either make our own
Universities Australia
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Universal Grammar is a universal grammar
Language is the most distinctive feature of humans, but there is no consensus on what is characteristic of language. From the point of view of computing, we argue that ‘the human brain circuitry that implements language is Turing complete’. This thesis makes evolutionary sense and natural languages are expressive enough, but two issues against it ...
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Are the New British Universities Congested? [PDF]
This paper uses data envelopment analysis (DEA) to examine the issue of congestion in British universities. The focus of the paper is on 41 former polytechnics that became universities in 1992, and the analysis covers the period 1995/6 to 2003/4.
Tony Flegg, David O. Allen
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Making a difference : Developing an evolving compendium of learning from SUII Projects to increase the impact of research on public policy and practice [PDF]
The Scottish Universities Insight Institute (SUII) supports collaborative and interdisciplinary programmes of knowledge exchange, which address and provide insights on substantial issues that face Scotland, and the wider world.
Scottish Universities Insight Institute
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

