Results 111 to 120 of about 137,024 (299)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Did the D.C. Tuition Assistance Grant Program Cause Out-of-State Tuition to Increase? [PDF]

open access: yes
The District of Columbia Tuition Assistance Grant (DCTAG) program is a federally funded financial aid program that allows District residents to pay in-state tuition rates at public colleges and universities throughout the United States.
Yuexing Lan, John V Winters
core  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

IFO Master Agreement MnSCU 1999-2001

open access: yes, 1999
This is the master agreement between the Inter Faculty Organization (IFO) and the Minnesota State Colleges and Universities (MnSCU) for the years 1999-2001. This is the labor contract between the Minnesota State University faculty and the Minnesota State
Inter Faculty Organization-Minnesota State Colleges & Universities   +1 more
core  

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

Identification and Expression Pattern Analysis of Cuticular Protein Gene Family in Monochamus alternatus (Coleoptera: Cerambycidae)

open access: yesBiology
The pine sawyer beetle (Monochamus alternatus Hope, 1842) is a major vector of the pinewood nematode [Bursaphelenchus xylophilus (Steiner & Buhrer, 1934) Nickle, 1970]. A total of 119 cuticular protein (CP) genes were identified from the M.
Xiaoman Ning   +3 more
doaj   +1 more source

IFO Master Agreement MnSCU 2011-2013

open access: yes, 2011
This is the master agreement between the Inter Faculty Organization (IFO) and the Minnesota State Colleges and Universities (MnSCU) for the years 2011-2013. This is the labor contract between the Minnesota State University faculty and the Minnesota State
Inter Faculty Organization-Minnesota State Colleges & Universities   +1 more
core  

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

Transcriptomics and Metabolomics Analysis Reveal the Mechanism of Petal Number Variation in Gardenia jasminoides

open access: yesMetabolites
Background/Objectives: This study was based on the joint analysis of transcriptome and metabolome to explore the key genes and metabolic pathways of gardenia single flower petal number variation and to explore the possible mechanism of floral organ ...
Bo Gao   +7 more
doaj   +1 more source

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