Results 91 to 100 of about 104,996 (303)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

CT community colleges; Connecticut community-technical colleges

open access: yes, 2011
Updated irregularly; Title from home page (publisher's Web site, viewed Apr. 12, 2011).; Official website of the Connecticut Board of Trustees of the Community-Technical Colleges.

core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Pollen and Floral Organ Morphology of 18 Oil-Tea Genotypes and Its Systematic Significance

open access: yesHorticulturae
Oil-tea belongs to the Camellia genus, an important oil crop in China. However, oil-tea is taxonomically challenging due to its morphological variation, polyploidy, and interspecific hybridization.
Qian Yin   +6 more
doaj   +1 more source

From the ground up: General Education Reform in Hong Kong

open access: yes, 2009
In 2004–2005, the government of Special Administrative Region of Hong Kong authorized a major reform of its universities-transitioning from a three-year undergraduate degree program focused exclusively on preparation in a focal profession or academic ...
Leung, MY   +3 more
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Scientific Methods and Sacred Matters: On Methodological Naturalism, Divine Agency, and Christians in Science

open access: yesZygon
This article critically analyzes the debate surrounding methodological naturalism (MN) within the context of scientific inquiry, focusing on the arguments put forth by Andrew Torrance on the one hand and John Perry and Sarah Lane Ritchie on the other. It
Mitchell Mallary
doaj   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The complete chloroplast genomes of four Aspidopterys species and a comparison with other Malpighiaceae species

open access: yesScientific Reports
The genus Aspidopterys has multiple functions in medicine, food and ecological restoration. Due to the similar morphological characteristics of some species and the limited genomic information hinder the studies on germplasm identification and molecular ...
He Liao, Huayuan Chen, Shinan Liu
doaj   +1 more source

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