Results 171 to 180 of about 81,715,714 (308)

Research Reality in Neuroradiology: a Survey Analysis at German University Hospitals. [PDF]

open access: yesClin Neuroradiol
von Tresckow BM   +10 more
europepmc   +1 more source

University Hospitals General Staff Meeting, April 27, 1933

open access: yes, 1933
University of Minnesota. University of Minnesota Hospitals. (1933). University Hospitals General Staff Meeting, April 27, 1933.
University of Minnesota. University of Minnesota Hospitals
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, March 7, 1935

open access: yes, 1935
University of Minnesota. University of Minnesota Hospitals. (1935). University Hospitals Staff Meeting Bulletin, March 7, 1935.
University of Minnesota. University of Minnesota Hospitals
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Network research management in Federal University Hospitals

open access: yesCogitare Enfermagem
Objective: To understand the aspects that impact on research management at the Brazilian Hospital Services Company (Ebserh). Methods: Experience report, carried out in the second half of 2022, online, with the application of Focus Group with research ...
Graciele de Matia   +5 more
doaj  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

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