Results 21 to 30 of about 1,177,514 (265)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

In the pursuit of sustainable library model – on the example of the UWM University Library's activities in Olsztyn

open access: yesForum Bibliotek Medycznych
In the third decade of the 21st century, the guidelines of sustainability have become a guarantor of care for the natural goods, social and economic balance, and cultural heritage of modern society.
Katarzyna Bikowska
doaj   +1 more source

ON THE FULL-FLEDGED MISSION STATEMENT OF THE UNIVERSITY SCIENTIFIC LIBRARY

open access: yesUniversity Library at a New Stage of Social Communications Development, 2021
The mission statement of an organization compiled in accordance with the definition of the term “mission” of the dictionary of the ISO 9000 quality management systems standard cannot be recognized as an effective management tool, since the ISO ...
Vladimir S. LAZAREV, Inna V. YURIK
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Die Medizinische Hauptbibliothek an der Goethe-Universität in Frankfurt am Main / The Medical Library at the Goethe University in Frankfurt am Main

open access: yesGMS Medizin – Bibliothek – Information, 2009
The history of the Medical Library begins in 1908, six years before the Frankfurt University was founded. Formerly it was a municipal establishment until 2005 it became a faculty library of the University Library and now belongs to the Frankfurt Goethe ...
Krüger, Hiltraud C.
doaj  

Bilkent Üniversitesi Kütüphanesi : Türk Plastik Sanatlar Arşivi / Bilkent University Library : Turkish Plastic Arts Archive [PDF]

open access: yesBilgi Dünyası, 2004
The present paper describes the Turkish Plastic Arts Archive at the Bilkent Univiersity Library. Its foundation, development, nature of services and aims to be followed were explained in detail.
Şelale Korkut
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Use of University’s Library Websites in Pakistan

open access: yesPakistan Journal of Information Management & Libraries, 2013
This study presents findings from a user-based evaluation of the use of Pakistani university's library websites. A questionnaire [printed and electronic] was used to collect the data from 17 universities.
Muhammad Ijaz Mairaj
doaj  

Identifying and Implementing Relevant Research Data Management Services for the Library at the University of Dodoma, Tanzania

open access: yesData Science Journal, 2020
Research Data Management (RDM) services are increasingly becoming a subject of interest for academic and research libraries globally – this is also the case in developing countries.
Gilbert Exaud Mushi   +2 more
doaj   +1 more source

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