Results 31 to 40 of about 1,177,514 (265)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
高校合併後圖書館的現狀分析及在學院管理模式下的應對舉措 Analysis on University Libraries after Colleges Incorporated and Its Impact of the New Management Model) [PDF]
Jiàoyù zīliào yǔ túshūguǎn xué, 2004 1992-2002年期間，我國共有700餘所普通和成人類的高校參加了這一期間的高校大合併，高校圖書館作為高校的重要資產也參加了這場合併與重組。本文根據相關資料簡要分析一下高校合併後的圖書館現狀及在高校學院管理模式下的應對舉措。During the period of 1992-2002, more than 700 colleges had been incorporated in China.
Li Guangdu
doaj
GMS Medizin – Bibliothek – Information, 2018 Libraries of Austrian universities – federal universities, private universities and universities of applied sciences – as well as libraries of other research facilities cooperate in many fields.
Bauer, Bruno
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
University and Public Libraries in the Virtual World between Reality and Future Prospects
دراسات: العلوم التربوية, 2020 This study deals with the existence of libraries and their curators in the virtual world, which is open and available for all users of the internet.
Ibrahim Khalil Khader
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University Library at a New Stage of Social Communications Development, 2020 Objective. This study aims 1) to acquire new information on alternative conference formats, including in the field of Library and Information Science (LIS), which have arisen as a result of the COVID-19 pandemic and restrictions on physical communication;
Tetiana O. KOLESNYKOVA
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2009 The Medical Library (Fachbibliothek Medizin (FBM)) was founded in 1969 as a Department of the Central University Library (Zentralbibliothek), and is located within the grounds of the University Medical Center in Mainz.
Geisel, Heike, Schweizer, Stefanus
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source