Results 91 to 100 of about 399,066 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Special Libraries, November 1936 [PDF]

open access: yes, 1936
Volume 27, Issue 9https://scholarworks.sjsu.edu/sla_sl_1936/1008/thumbnail ...
Special Libraries Association
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Assessing the Fitness of an Academic Library for Doctoral Research

open access: yesEvidence Based Library and Information Practice, 2014
Objective – At the University of California, Berkeley (UCB), researchers compared how well the library collections supported doctoral research in the three related disciplines of education, psychology, and social welfare. The goal of this project was to
Susan Edwards, Lynn Jones
doaj  

International print and digital repositories initiatives in the United States: CRL, Portico, LOCKSS, Internet Archive : print archives in the United States [PDF]

open access: yes, 2006
A number of pressures on academic libraries imperil the long-term survivability of printed knowledge and heritage materials. Ever-growing volumes of materials, costs of preserving and delivering paper-based research resources, and researchers’ growing ...
Simon, James
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Customizing Alma and Primo for Home & Locker Delivery

open access: yesCode4Lib Journal, 2021
Like many Ex Libris libraries in Fall 2020, our library at California State University, Northridge (CSUN) was not physically open to the public during the 2020-2021 academic year, but we wanted to continue to support the research and study needs of
Christina L. Hennessey
doaj  

An International Prospectus for Library & Information Professionals: Development, Leadership and Resources for Evolving Patron Needs [PDF]

open access: yes, 2007
The roles of library and information professionals must change and evolve to: 1. accommodate needs of tech-savvy patrons; 2. thrive in the Commons & Library 2.0; 3. provide integrated, just-in-time services; 4. constantly update and enhance technology; 5.
Bailey, D. Russell
core   +1 more source

Using Your Library’s Objectives as the Organizational Framework for Library Documentation in Planning, Assessment, and Accreditation

open access: yes, 2016
The San Diego Christian/Southern California Seminary Library1 uses its objectives as the organizational framework for its strategic plan, annual report, assessment plan, and policies and procedures manual.
Ewing, Jennifer S., Martin, Ruth E.
core   +1 more source

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