Results 111 to 120 of about 399,066 (305)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The Activities and Program of the American Association of Law Libraries [PDF]

open access: yes, 1936
Denna rapport kommer att behandla konstruktion och design av ett småskaligt portabelt solvärmesystem. Rapportens första del är en teoretisk referensram som ligger till grund för byggandet av en prototyp av den behandlade solvärmetypen som har testats för
Klasson, Hanna   +4 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Science Librarianship and Social Justice: Part One Foundational Concepts

open access: yesIssues in Science and Technology Librarianship, 2020
Jeffra Bussmann   +4 more
doaj   +1 more source

Special Libraries, September 1966 [PDF]

open access: yes, 1966
Volume 57, Issue 7https://scholarworks.sjsu.edu/sla_sl_1966/1006/thumbnail ...
Special Libraries Association
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Guidelines of discussion board prompts in higher education: A scoping review protocol

open access: yesInternational Journal of Educational Research Open
Background & Aim: Discussion boards are a key component of online courses in higher education. Educators use this collaborative environment to encourage social and intellectual interactions, develop reasoning and presentation skills, and facilitate ...
Denise R. Gehring   +3 more
doaj   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih   +40 more
wiley   +1 more source

The Perceived Concerns of Nurse Educators' Use of GenAI in Nursing Education: Protocol for a Scoping Review

open access: yesHealth Science Reports
Background/Aims Since the emergence of generative AI (GenAI) in fall 2022, its impact on higher education has been significant yet under‐researched, leading to mixed reactions among nurse educators, ranging from enthusiasm to skepticism.
Denise R. Gehring   +2 more
doaj   +1 more source

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