Results 61 to 70 of about 2,213,233 (256)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal of Education, Health and Sport, 2016 Jarecka Paulina, Fąk Tadeusz. Wiedza o zdrowiu a aktywność fizyczna w stylu życia uczestników Uniwersytetów Trzeciego Wieku na przykładzie Wrocławia = Knowledge about health and physical activity in life style among students of Universities of the ...
Paulina Jarecka, Tadeusz Fąk
doaj +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Elderly: A New Social Actor ahead of the finitude/death
Kairós Gerontologia, 2014 Longevity is one of humanity’s greatest conquests, however the aging process and old age itself are still filed with stereotypes and negative stigmas. Despite all of the prejudice suffered by the elderly in the Brazilian culture, this age group has been ...
Rita de Cássia da Silva Oliveira +2 more
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The neuropsychology of healthy aging: the positive context of the University of the Third Age during the COVID-19 pandemic. [PDF]
Sci Rep, 2023 Amanzio M +6 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The impact of the COVID-19 pandemic on well-being of seniors attending online programs at University of the Third Age: a follow-up study. [PDF]
Psychogeriatrics, 2022 Kayhan Koçak FÖ +3 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Psychology Research and Behavior Management, 2020 Małgorzata Szcześniak, Grażyna Bielecka, Daria Madej, Elżbieta Pieńkowska, Wojciech RodzeńInstitute of Psychology, University of Szczecin, Szczecin 71-017, PolandCorrespondence: Małgorzata Szcześniak Email malgorzata.szczesniak@usz.edu.plBackground: The ...
Szcześniak M +4 more
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