Results 71 to 80 of about 2,213,233 (256)

Physical activity and quality of life according to students of the University of the Third Age

open access: yesAdvances in Rehabilitation, 2017
Introduction: Along with the rising life expectancy, there occurs an increased interest in geriatric care and in assessment of life quality in elderly persons.
Skwiot Marlena   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Education for whom and why? Managing the educational process of senior citizens

open access: yesHoryzonty Wychowania, 2019
RESEARCH OBJECTIVE: Determine student programme preferences in the context of a diagnosis of their behaviour in terms of maintaining good health. THE RESEARCH PROBLEM AND METHODS: How may the educational process be organized?
Żanetta Kaczmarek
doaj  

Active Ageing Through Lifelong Learning: The University of the Third Age

open access: yes, 2019
The World Health Organization defined ‘active ageing’ as the process of optimising opportunities for health, participation and security in order to enhance the quality of life as people age. Whilst initially active ageing was hinged upon the three pillars of health, participation and security, in more recent years lifelong learning was posited as an ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Education and socialisation in later life: The case of a University of Third Age in Portugal

open access: yesEuropean Journal for Research on the Education and Learning of Adults, 2019
In recent years, researchers have become increasingly interested in studying various dimensions of ageing and learning based on various disciplinary approaches.
Andrea Porcarelli, Rute Ricardo
doaj   +1 more source

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