Results 111 to 120 of about 1,348,891 (290)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
DCU-TCD@LogCLEF 2010: re-ranking document collections and query performance estimation [PDF]
, 2010 This paper describes the collaborative participation of Dublin City University and Trinity College Dublin in LogCLEF 2010. Two sets of experiments were conducted. First, different aspects of the TEL query logs were analysed after extracting user sessions
Ghorab, M. Rami +4 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Internationale Hochschulrankings: Ein methodenkritischer Vergleich [PDF]
, 2018 Zusammenfassung: Trotz ihrer umstrittenen Validität, Zuverlässigkeit und Wirkung, werden internationale Universitätsrankings immer häufiger von Studierenden und Universitäten als Informationsquellen genutzt.
Daniel, H. -D, Kroth, Anna
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
La UC3M sube 41 posiciones en el Ranking QS [PDF]
, 2015 Enlace al Ranking QS en: http://www.topuniversities.com/university-rankings/world-university-rankings/2015#sorting=rank+region=+country=+faculty=+stars=false ...
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
COMPETITIVE ADVANTAGES OF THE NATIONAL HIGHER EDUCATION SYSTEM IN THE CONTEXT OF GLOBALIZATION
Economics & Education, 2016 The article reveals the essence and types of competitive advantages of the national higher education system. It features the analysis and assignation of priorities of formation of functional and structural competitive advantages of the higher education ...
Iryna Kalenuk
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Internationalization of Universities as Internationalization of Bildung [PDF]
Internationalization receives top priority in nearly any university mission state-ment. But why? What is the value of internationalization for a university?
Lenz, Rainer, Steinhaus, Carol
core +1 more source