Results 81 to 90 of about 391,712 (285)

"On the Robustness of Alternative Rankings Methodologies For Australian and New Zealand Economics Departments" [PDF]

Just as friendly arguments based on an ignorance of facts eventually led to the creation of the definitive Guinness Book of World Records, any argument about university rankings has seemingly been a problem without a solution.
Dipendra Sinha, Joseph Macri, Michael McAleer   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Funding for China’s Top Universities: Does Size Matter?

Высшее образование в России
Over the past thirty years, thanks to government initiatives for the “construction” of world-class universities, a cohort of elite (leading) universities has been created in China, covering about 5 % of universities, which have tangible advantages over ...
S. S. Donetskaya, Liang Bin
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The international and national university rankings as an constituent of university`s competitiveness [PDF]

Marketing i Menedžment Innovacij, 2016
The aim of the article. The aim of the article is to define the importance of participation in World or National universities rankings for higher university institutions as an effective tool in development and improvement of higher education system in ...
Yu.S. Shypulina, O.F. Gryshchenko, V.O. Bilenko   +2 more
doaj  

University rankings in action? The importance of rankings and an excellence competition for university choice of high-ability students? [PDF]

This paper analyzes how high-ability students respond to different indicators of university quality when applying for a university. Are some quality dimensions of a ranking, e.g. research reputation or mentoring more important than others?
Horstschräer, Julia
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The mismeasure of higher education? The corrosive effect of university rankings

Ethics in Science and Environmental Politics, 2013
This paper examines the limitations and biases of world university rankings and asks what drivers explain their ongoing proliferation and popularity. It is argued that rankings are having a corrosive effect on higher education systems, institutions and ...
D Robinson
doaj   +1 more source

The 2017 University Metaranking. Romanian University Ranking

Journal of Research in Higher Education, 2018
This article continues the work done for the 2016 University Metaranking and updates its results for the 2017 edition, with the new data available for 2017. The 2017 University Metaranking relies on the results of the performance of Romanian universities in international league tables / rankings in the field of higher education.
Daniel David, Ovidiu Andronesi, Carmen Buzea, Bogdan Florian, Silviu Matu, Lazăr Vlăsceanu   +5 more
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source