Results 41 to 50 of about 3,827,148 (296)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Educar para corregir una actitud de los universitarios: el fideísmo Educar para corrigir uma atitude de faculdade: o fideísmo Education to Correct an Attitude among University Students and Teachers: Fideism

open access: yesEducación y Educadores, 2009
En este trabajo se desvela el error de una actitud educativa que acepta taimadamente el "fideísmo": actitud que afecta a muchos universitarios -docentes y discentes- que quieren ser y se consideran a sí mismos como hombres "buenos". Se describe la índole
Juan Fernando Selles
doaj  

Study and research courses and mathematical modelling in the natural sciences university teaching

open access: yesEnseñanza de las Ciencias, 2011
This paper focuses on the role of mathematical modelling in first year courses of experimental sciences university degrees. Within the frame of the Anthropological Theory of the Didactic, we propose the design and implementation of «Study and Research ...
Berta Barquero i Farràs   +2 more
doaj   +1 more source

What works?: the culture of evidence in university teaching [PDF]

open access: yes, 2017
This article analyses the culture of evidence in university teaching and its implications in the professional training of teachers in higher educa tion. The new culture of organisati on and assessment introduced into
Heras Monastero, Bárbara de las   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Involving students in teaching: analysis of an educational innovation pathway at University

open access: yesFormare, 2018
This paper describes the teaching innovation process as it was tested in one of the University courses through the adoption of a methodological approach based on the constructivist approach.
Graziano Cecchinato   +1 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Pratiques in situ d’enseignants-chercheurs et confrontation avec le vécu des étudiants : une étude de cas en mathématiques et en physique

open access: yesAnnales de Didactique et de Sciences Cognitives
This research focuses on the teaching practices of teacher-researchers (TRs) in a lecture context. Their declared practices were studied using the sociological notion of professional identity.
Stéphanie Bridoux   +2 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

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